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This review examines current knowledge on human epithelial hair follicle stem cells, their markers, and outlines challenges in translating findings from murine studies to human research, but does not report new experimental results.

This review discusses the molecular mechanisms of androgens and androgen receptors in skin disorders, particularly androgenetic alopecia, and reports no new clinical results; it highlights potential areas for future treatment development.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

This study found that in healthy men, higher levels of free testosterone were associated with a stronger immune response to the influenza vaccine, suggesting androgens may function as immunomodulators rather than strict immunosuppressants.

This study found that liposomal formulations improved minoxidil delivery to skin layers compared to niosomes and a control solution, suggesting enhanced potential for topical hair loss treatment.

This study found that downregulation of EGF and KGF signaling is necessary for hair follicle initiation in placodes, revealing a new role for KGF in hair follicle formation in mice.

This review discusses the shedding phase of the hair cycle, known as exogen, and reports no new findings while analyzing related processes like club fiber formation and release.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

This consensus document provides foundational position statements for dermatologic ultrasound but reports no clinical results; it aims to guide future evidence-based recommendations and guidelines.

This case report describes a 10-month-old boy with dermatitis, alopecia, and hypotonia who showed dramatic improvement with oral biotin, suggesting a possible defect in biotin absorption or transport.

This review discusses the potential role of steroid 5α-reductase inhibitors in treating neuropsychiatric disorders related to dopaminergic hyperreactivity but reports no new clinical results.

This review highlights how advanced nanocarrier and microneedle-based transdermal drug delivery strategies can potentially improve the treatment of skin diseases by enhancing site-specific drug delivery, increasing skin penetration, and reducing systemic toxicity compared to conventional methods.

In this study, blocking the CXCR3 receptor in mice prevented the development of alopecia areata by inhibiting the accumulation of specific T cells in the skin, suggesting a potential therapeutic approach for humans.

This review highlights the potential of coffee silverskin's bioactive compounds in combating skin aging and related conditions, suggesting it as a promising natural ingredient for cosmetics due to its antioxidant, anti-inflammatory, and anti-aging properties.

This review discusses current therapeutic targets and treatments for androgenic alopecia but reports no clinical results; the authors highlight the challenge of developing multi-target drugs for effective treatment.

In this study, researchers created a core-shell nanozyme, CeO2@ZIF-8/Au, which autonomously regulates ROS levels to efficiently eliminate bacteria, reduce inflammation, and promote wound healing by balancing ROS generation and scavenging in response to environmental conditions.

This study identified five mutations in the gene LSS in individuals with unexplained hypotrichosis simplex, highlighting a potential role of mislocalized LSS proteins in disrupting hair follicle biology.

This review highlights recent advancements in using nanotechnology to improve the function and delivery of PROTAC drugs, despite existing challenges like low solubility and poor permeability, aiming to enhance their potential in disease treatment.

This study found that Transcutol-containing vesicles improved the delivery of minoxidil to deeper skin layers in vitro but did not facilitate its permeation through the skin.

This review examines the role of steroidal inhibitors in treating prostatic diseases but presents no new clinical results.

This review discusses the development and selectivity of 5 alpha-reductase inhibitors, particularly non-steroidal ones, and reports no new clinical trial results.

This study found that minoxidil-loaded niosomes with a Span 60 and cholesterol ratio of 1:2 significantly increased skin retention of minoxidil compared to control gel.

This article reviews various strategies, primarily developed by the Turin University Pharmaceutical Technology group, for increasing entrapment efficiency of hydrophilic molecules in nanoparticulate systems and reports no clinical results.

This letter discusses the potential connection between androgenetic alopecia and COVID-19, suggesting a possible new therapy, but it reports no new results.

In this study, the authors concluded that COVID-19 may not cause direct long-term harm to testicular function, but temporary indirect effects could occur, suggesting a possible delay in pursuing parenthood post-recovery.

This study validated the VQ-Dermato, the first dermatology-specific quality of life instrument in French, and found it to be reliable, acceptable for routine use, and more responsive than the SF36.

This review discusses the role of phytochemical nanoparticles in cervical cancer therapy and reports no new clinical results; the authors highlight their potential advantages over conventional chemotherapy.

This review discusses advancements in the use of microneedle arrays and nanoparticles for transdermal delivery of therapeutics, noting challenges in overcoming the skin barrier and summarizing recent clinical trial achievements in areas like cancer therapy and gene therapy.

This study found that autophagy plays a novel role in human hair growth, with altered autophagic flux during hair development phases influencing hair follicle behavior in a preclinical model.

This study found that newly synthesized steroidal trienones demonstrated stronger 5α-reductase inhibitory activity compared to dienones in various biological models, suggesting potential for developing enhanced antiandrogenic drugs.