TLDR The nanoplatform helps heal wounds by balancing bacteria-killing and inflammation-reducing functions.
The study presents a core–shell nanozyme, CeO2@ZIF-8/Au, designed to regulate reactive oxygen species (ROS) levels for effective wound repair. This nanoplatform combines ROS generation and scavenging functions, allowing it to kill bacteria, reduce inflammation, and promote healing. The Au nanoparticles on the shell generate ROS to eliminate bacteria, while the CeO2 core, initially encapsulated by ZIF-8, is gradually released in acidic environments to scavenge excess ROS. This dual function ensures a balanced ROS level, highlighting the potential of this technology in developing advanced antibacterial therapies.
4 citations
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December 2023 in “Advanced science” New injectable hydrogels with gelatin, metal, and tea polyphenols help heal diabetic wounds faster by controlling infection, improving blood vessel growth, and managing oxidative stress.
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October 2022 in “Nano Letters” Machine learning identified promising nanozymes for treating hair loss.
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November 2023 in “Nano-Micro Letters” Nanozymes show promise for effective and safe cancer treatment.
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November 2021 in “Frontiers in Chemistry” Nanozymes could improve disease treatment and detection.
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January 2022 in “Polymers” Nanoparticles added to natural materials like cellulose and collagen can improve cell growth and wound healing, but more testing is needed to ensure they're safe and effective.
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25 citations
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November 2022 in “Frontiers in Bioengineering and Biotechnology” Composite biodegradable biomaterials can improve diabetic wound healing but need more development for clinical use.
