Inorganic Nanozymes: Prospects for Disease Treatments and Detection Applications

    November 2021 in “ Frontiers in Chemistry
    Peng Wang, Dongyu Min, Guoyou Chen, Minghui Li, Liquan Tong, Yonggang Cao
    TLDR Nanozymes could improve disease treatment and detection.
    The document reviewed the potential of inorganic nanozymes as substitutes for natural enzymes in disease treatment and detection applications. Nanozymes, including metal oxide, noble metal, and carbon-based types, offered advantages such as stability under extreme conditions, lower production costs, and adjustable catalytic activity. They showed promise in medical applications like tumor therapy, antibacterial, antiviral, antifungal treatments, and inflammation reduction. Nanozymes demonstrated high sensitivity and broad-spectrum durability, making them promising alternatives to traditional methods. However, challenges such as low catalytic activity, biosafety concerns, and unclear mechanisms of action limited their clinical application. Future research was suggested to focus on enhancing enzyme activity, ensuring biosafety, and understanding the mechanisms of nanozymes to expand their therapeutic applications.
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