Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.
October 2021 in “Research Square (Research Square)” Hair follicle stem cells in hairpoor mice are disrupted, causing hair loss.
773 citations,
August 2017 in “International Journal of Molecular Sciences” The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
89 citations,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
44 citations,
April 2017 in “Genes & development” Scientists found cells in hair that are key for growth and color.
25 citations,
February 2019 in “Genomics” Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.
20 citations,
September 2021 in “Nature communications” Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
19 citations,
April 2015 in “European Journal of Pharmacology” Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
16 citations,
July 2021 in “Histopathology” New markers and pathways have been found in skin tumors, helping better understand and diagnose them.
14 citations,
September 2018 in “International Journal of Molecular Sciences” Mackerel-derived fermented fish oil helps hair grow by activating growth pathways and increasing cell proliferation.
13 citations,
September 2020 in “International Journal of Molecular Sciences” PRP therapy and minoxidil combo works best for male hair loss.
13 citations,
March 2017 in “Genomics” Genomic approach finds new possible treatments for hair loss.
13 citations,
November 2013 in “Journal of Endocrinology/Journal of endocrinology” Vitamin D receptor helps control hair growth genes in skin cells.
12 citations,
December 2009 in “Amino Acids” Putting α-methylspermidine on mouse skin can start hair growth.
9 citations,
January 2018 in “Stem Cells International” Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.
4 citations,
August 2020 in “Applied Materials Today” Hydrogel microcapsules help create cells that boost hair growth.
3 citations,
April 2011 in “Expert Review of Dermatology” Male hair loss is caused by inactive hair follicle stem cells.
2 citations,
September 2022 in “Frontiers in veterinary science” Certain long non-coding RNAs are important for the growth of hair follicles in Inner Mongolian cashmere goats.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
November 2023 in “Food science of animal resources” Lactilactobacillus curvatus LB-P9 taken orally helps hair regrow faster and thicker in mice.
September 2023 in “Frontiers in medicine” The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
June 2023 in “Livestock studies” The article concludes that understanding the molecular processes in hair follicle development can improve the quality of fibers like Angora and cashmere.
November 2022 in “Gigascience” A specific genetic deletion in goats affects cashmere yield and thickness.
September 2020 in “Research Square (Research Square)” Researchers found that certain RNA sequences play a role in yak hair growth and these sequences are somewhat similar to those in cashmere goats.
April 2019 in “Journal of Investigative Dermatology” Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.
81 citations,
October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain genes control the color of human hair by affecting pigment production.
24 citations,
December 2018 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
3 citations,
November 2014 in “Protein Expression and Purification” Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.
16 citations,
July 2019 in “Journal of Cellular Biochemistry” Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
82 citations,
March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.