research Stromal Re-Organization in Hair Follicle Development and Cancer Suppression
Activating Sonic Hedgehog signaling in cancer stroma may help treat basal cell carcinoma.
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research Human TSC2-Null Fibroblast-Like Cells Induce Hair Follicle Neogenesis and Hamartoma Morphogenesis
Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Pearly Pinna Papules in a Young Female
The young woman has a benign, hereditary skin condition with no signs of a more serious syndrome.
research Hair Follicle Regeneration Using Grafted Rodent and Human Cells
Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
research Growth Factors in Hair Organ Development and the Hair Growth Cycle
Growth factors are crucial for hair development and could help treat hair diseases.
research Estrogen Functions in Skin and Skin Appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research FLCN, A Novel Autophagy Component, Interacts With GABARAP And Is Regulated By ULK1 Phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Macrophage Ferroportin Is Essential for Stromal Cell Proliferation in Wound Healing
Macrophage iron release is crucial for hair growth and wound healing.
research Neuregulin3 Alters Cell Fate in the Epidermis and Mammary Gland
Neuregulin3 affects cell development in the skin and mammary glands.
research PPAR-γ Signaling as a Key Mediator of Human Hair Follicle Physiology and Pathology
PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
research Direct Cellular Reprogramming Enables Development of Viral T Antigen-Driven Merkel Cell Carcinoma in Mice
Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.
research The Eye and the Skin in Endocrine Metabolic Diseases
Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.
research Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease
Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
research RSPO1-Mutated Keratinocytes From Palmoplantar Keratoderma Display Impaired Differentiation and Invasiveness: Implications for Squamous Cell Carcinoma Susceptibility in Patients With 46XX Disorder of Sexual Development
RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
research A Kaleidoscope of Keratin Gene Expression and the Mosaic of Its Regulatory Mechanisms
Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
research Characteristics of KRT80 and Its Roles in Neoplastic Diseases
KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.
research Dermatologic Care of the Transplant Patient
Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.
research Diseases Of The Canine Prostate Gland
The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.
research The Thrill of Scientific Discovery and Leadership with My Group
The author felt excited and honored to receive the 2016 Early Career Life Scientist Award.
research An EGFP-Col4a2 Mouse Model Reveals Basement Membrane Dynamics Underlying Hair Follicle Morphogenesis
Basement membrane changes are crucial for hair follicle development.
research Large-Scale Preparation of Hair Follicle Germs Using a Microfluidic Device
A new method using a microfluidic device can prepare hair follicle germs efficiently for potential use in hair loss treatments.
research Wound Healing Induced Hair Follicle Regeneration
New hair can grow at wound sites, which could help improve treatments for hair loss and wound healing.
research The Evolutionary Impact of Androgen Levels on Prostate Cancer in a Multi-Scale Mathematical Model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
research Expression Characteristics of BMP2, BMPR-IA, and Noggin in Different Stages of Hair Follicle in Yak Skin
BMP2 and BMPR-IA may stop hair growth while Noggin may encourage it in yak skin.
research Regulatory T Cells in Skin Regeneration and Wound Healing
Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
research Early Leonine Facies with Alopecia in a Young Man
A young man was diagnosed with trichoepitheliomas, causing thick skin and hair loss.
research Cutaneous Side Effects of Chemotherapy and Radiotherapy
Chemotherapy and radiotherapy can cause skin side effects like rashes, hair loss, and nail changes, which are usually managed with conservative treatments.
research Hirsutism as the Initial Presentation of Malignant Ovarian Leydig Cell Tumor: A Case Report
A woman's male-pattern facial hair growth was caused by a rare malignant ovarian tumor that was difficult to diagnose and treat.
research Mammary Cells with Active Wnt Signaling Resist ErbB2-Induced Tumorigenesis
Cells with active Wnt signaling are less likely to turn into cancer when exposed to a cancer-causing gene.