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Epidermal stem cells show promise for treating orthopedic injuries and diseases.

Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.

Researchers found specific genes in the part of hair follicles that could help treat hair disorders.

Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

Androgens can cause hair growth in some areas but hair loss on the scalp.

The conclusion suggests that focusing on certain cellular pathways may improve the prevention and repair of hair loss caused by radiotherapy.

Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.

Claudin-1 is important for the barrier function and growth of hair.

Notch-related genes play a key role in the development and cycling of hair follicles.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Hydra can help understand human hair follicle microbiomes and develop new skin disease therapies.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Using defensins to activate stem cells may improve skin aging signs without causing inflammation.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Hair color is determined by different melanins and changes with age.

Dermal papilla cells help wounds heal better and can potentially grow new hair.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.

A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Targeting NETs may help reduce fibrosis in Crohn's disease.

ILC1-like cells can cause alopecia areata by attacking hair follicles.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.