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This review examines the literature on the molecular and cellular makeup of the hair follicle niche and how it influences stem cell behavior during hair regeneration, but does not provide new experimental results.

This study found that the Ovol2-Zeb1 regulatory circuit is crucial for controlling directional migration and proliferation in epithelial cells, facilitating skin regeneration and repair in mice.

This study found that the Foxn1(-/-) nude phenotype significantly influences epithelial progeny in skin, with notable changes in stem cell niches not achievable in other models.

In this study with mice, simultaneous inactivation of Smad4 and PTEN genes led to rapid development of invasive forestomach squamous cell carcinomas, mirroring human esophageal SCCs.

In this study, the deletion of Smad4 and PTEN genes in mice was associated with rapid and invasive squamous cell carcinoma formation in the forestomach, modeling human esophageal cancer progression.

This study suggests that epithelial-derived pop-up keratinocytes (ePUKs) may improve regenerative medicine applications due to their specific phenotype and increased expression of proteins involved in regulating cellular movement and wound healing.

This study in SPF lambs found that primary and secondary orf virus infections trigger similar skin responses, but the primary infection caused a more severe and prolonged reaction.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

In this study, researchers developed a method to differentiate human iPSCs into cells that can generate all lineages of hair follicles, potentially aiding treatments for hair loss and skin disorders.

This article reviews methods to enhance epithelial–mesenchymal interactions for hair follicle bioengineering but does not present new experimental results; it emphasizes optimizing combinations for successful regeneration.

This study found that FOXN1 haploinsufficiency is a significant genetic factor causing T cell lymphopenia at birth, linked to reduced thymic function in both humans and mice.

This case report and literature review describes a 27-year-old woman with a Sertoli Leydig cell tumor causing testosterone-related symptoms and highlights normalization of hormone levels after surgical treatment.

This study found that Sox2 and BMP signaling may be key regulators of pigmentation and melanocyte migration, as suggested by experiments in mice, human biopsies, and cell co-cultures.

This study found that ILK deficiency disrupts hair follicle development by impairing cell polarity and laminin-511 assembly, but these defects can be partially reversed with exogenous laminin-511.

In this study, dihydroartemisinin reduced prostate enlargement and related markers in a rat model of benign prostatic hyperplasia, suggesting its potential as a therapeutic agent.

This study found that PHBV cocultured with epithelial and dermal cells might enhance early-stage wound healing by promoting wound closure and re-epithelization more effectively than PHBV/collagen.

This research found that deleting the SLC3A2 gene in hair follicle stem cells disrupts their maintenance and proper differentiation, leading to hair follicle growth defects and altered skin regeneration through a YAP/Taz-dependent pathway.

This study found that inhibiting AP-1 activity in mice modified tumor development, leading to transdifferentiation between squamous and sebaceous tumors, with molecular analysis suggesting AP-1's role in maintaining tumor cell identity.

This study found that Secretory Phospholipase A2-IIA (sPLA2-IIA) promotes proliferation through JNK/c-Jun signaling, distinctively affecting normal stem cells and cancer cells, suggesting it as a potential target for cancer treatment.

This study found that chitosan nanoparticles containing Cordyceps militaris effectively reduced lung damage in mice exposed to fine particulate matter (PM2.5) by decreasing oxidative stress and preserving lung barrier integrity, suggesting potential as a therapeutic candidate for PM2.5-induced lung diseases.

This article reviews historical reports of skin changes, such as pseudoacanthosis nigricans, associated with cholesterol-lowering drugs like triparanol and nicotinic acid, but presents no new clinical findings.

This study found that acne inversa is primarily an epithelial-driven disease, with cyst-forming tendrils causing inflammation due to rupture and the release of debris, highlighting limitations of punch biopsies for analysis.

Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.

This review discusses the molecular mechanisms driving hair follicle degeneration in skin aging and emphasizes the role of the tissue microenvironment on stem cell function, but reports no new research findings.

This study found that fibronectin supports hair follicle regeneration by influencing stem cell behavior through integrin-dependent mechanotransduction, highlighting its potential role in epidermal renewal.

This review summarizes the current understanding of microRNAs in skin biology, highlighting their roles in processes like wound-healing and aging, without presenting any new experimental results.

This review discusses lung regeneration and highlights the role of facultative stem/progenitor cells, but it reports no new findings and calls for further exploration of underlying mechanisms.

This study found that high-dose radiation can induce accelerated cellular senescence, inflammation, and loss of epithelial stem cells in mouse and human skin, contributing to radiation dermatitis.

This study found that a mutation causing Stormorken syndrome in mice led to skeletal abnormalities and unusual hair growth, showcasing the STIM1 R304W protein’s role in bone development and cell fate.