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    Histologic Progression of Acne Inversa/Hidradenitis Suppurativa: Implications for Future Investigations and Therapeutic Intervention

    January 2021 in “ Experimental dermatology ”
    Robert W. Dunstan, K. Salte, Viktor Todorović … Prisca Honoré
    Studysummary This study found that acne inversa is primarily an epithelial-driven disease, with cyst-forming tendrils causing inflammation due to rupture and the release of debris, highlighting limitations of punch biopsies for analysis.
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    Research cited in this study 11

    1. Keratin 17 in Disease Pathogenesis: From Cancer to Dermatoses Journal of pathology · 2018
    2. Dissecting Folliculitis (Dissecting Cellulitis) of the Scalp: A 66-Patient Case Series and Proposal of Classification Journal der Deutschen Dermatologischen Gesellschaft · 2018
    3. Acne and Hidradenitis Suppurativa British journal of dermatology/British journal of dermatology, Supplement · 2018
    4. Mechanical Stress and the Development of Pseudo-Comedones and Tunnels in Hidradenitis Suppurativa/Acne Inversa Experimental Dermatology · 2016
    5. Deciphering the Functions of the Hair Follicle Infundibulum in Skin Physiology and Disease Cell and Tissue Research · 2014
    6. Keratin K15 as a Biomarker of Epidermal Stem Cells International Journal of Molecular Sciences · 2013
    7. Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology Experimental dermatology · 2013
    8. Expression of the Hair Stem Cell-Specific Marker Nestin in Epidermal and Follicular Tumors PubMed · 2008
    9. Viewpoint 4 Experimental Dermatology · 2008
    10. Variations of Hair Follicle Size and Distribution in Different Body Sites Journal of Investigative Dermatology · 2004
    11. Nestin Expression in Hair Follicle Sheath Progenitor Cells Proceedings of the National Academy of Sciences · 2003