March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.
2 citations,
April 2021 in “International Journal of Molecular Sciences” The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.
Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.
3 citations,
December 2020 in “Scientific reports” Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.
87 citations,
January 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
77 citations,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
1 citations,
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
85 citations,
December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
40 citations,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
13 citations,
March 2020 in “Frontiers in cell and developmental biology” A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
June 2018 in “Advances in Cosmetic Surgery” Hair loss caused by genetics and hormones; more research needed for treatments.
299 citations,
January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
4 citations,
November 2014 The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
103 citations,
November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
56 citations,
February 2012 in “Cell Cycle” MicroRNAs are crucial for controlling skin development and healing by regulating genes.
1 citations,
July 2016 in “Elsevier eBooks” Understanding skin structure and development helps diagnose and treat skin disorders.
277 citations,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
94 citations,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
90 citations,
June 2006 in “The American Journal of Dermatopathology” The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
20 citations,
January 2015 in “Current problems in dermatology” Graying hair happens due to aging and might be delayed by new treatments.
13 citations,
July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
1 citations,
January 2012 in “Elsevier eBooks” The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
98 citations,
February 2007 in “Seminars in Cell & Developmental Biology” Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
21 citations,
June 2016 in “Genesis” Researchers identified specific genes that are important for mouse skin cell development and healing.
13 citations,
January 2016 in “Journal of cosmetology & trichology” Alternative treatments show promise for hair growth beyond traditional methods.
3 citations,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
55 citations,
December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
10 citations,
May 2016 in “Journal of Dermatological Science” PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
96 citations,
June 2017 in “Nature Communications” A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
48 citations,
March 2019 in “Frontiers in Physiology” Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.