TLDR Tranexamic acid reduces skin aging more in female mice.
The study on hairless mice over 2 years found that tranexamic acid (12 mg/kg/day, three times a week) reduced signs of skin aging by inhibiting plasmin synthesis, increasing hyaluronic acid production, boosting epidermal cell numbers, and suppressing matrix metalloproteinase (MMP) activity, thus preserving the extracellular matrix (ECM). The effects were more pronounced in female mice, indicating a sex difference in the ameliorative effects of tranexamic acid on skin aging.
1 citations,
December 2023 in “Life” PRP helps skin heal, possibly through special cells called telocytes.
February 2024 in “International Journal For Multidisciplinary Research” Nanostructured lipid carriers are effective for treating hyperpigmentation in women aged 30-40.
10 citations,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
June 2023 in “NILES Journal forGeriatric and Gerontology/NILES Journal for Geriatric and Gerontology” Oral tranexamic acid is a safe and effective treatment for melasma.
January 2014 in “Journal of Cutaneous and Aesthetic Surgery” The document suggests that for better patient satisfaction in hair transplants, high-quality photos are needed, and using a narrow donor strip might lead to fewer grafts and dissatisfaction, but filling the scar with FUE grafts and using tranexamic acid can improve results.
