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research Itpr3 Is Responsible for the Mouse Tufted (tf) Locus
This study identified the Itpr3 gene as responsible for the tufted hair loss phenotype in the BTBR mouse strain.
research Injectable Thermosensitive Placental ECM –Copper Hydrogel With Endothelial Progenitor Cells for Pressure Ulcer Repair
This study found that a hydrogel made from human placenta-derived ECM, copper, and endothelial progenitor cells significantly enhanced pressure ulcer healing in a mouse model by improving wound closure and tissue regeneration.
research Discovery of a transdermally deliverable pentapeptide for activating AdipoR1 to promote hair growth
This study found that a 5-mer peptide called P5 promotes hair growth by activating adiponectin receptor 1, suggesting its potential use as a topical treatment for alopecia.
research Study of the biological function and penetration pathways of the mouse epidermal growth factor ethosomal delivery system
This study found that mEGF ethosomal delivery systems mainly penetrated mice skin through the pilosebaceous unit and successfully induced hair follicles to transition from the telogen to anagen phase.
research Erosive pustular dermatosis of the scalp treated with 0.1% mometasone furoate cream.
In this case report, erosive pustular dermatosis of the scalp in a 49-year-old man showed improvement with daily application of 0.1% mometasone furoate cream.
research Mechanisms of proton inhibition and sensitization of the cation channel TRPV3
This study found that acid regulation of the TRPV3 channel can inhibit its function from outside the cell while facilitating it from inside, providing insights into skin barrier and disorder mechanisms related to tissue acidosis.
research Equine Cushings Disease - PPID
This source explains that Equine Cushing’s disease, or PPID, in horses is due to the degeneration of brain cells producing dopamine, leading to elevated cortisol levels and characteristic symptoms; it outlines diagnosis methods and emphasizes life-long pergolide treatment to manage the condition.
research Evaluación pronóstica de la escala delta-sofa a los 3 y 5 días del ingreso en uci asociado al saps 3 y creación de un modelo objetivo para la adecuación ética del esfuerzo terapéutico
This study found that P144 (Disitertide) significantly reduced collagen deposition and improved muscle organization in a rabbit model of post-radiotherapy fibrosis, suggesting potential antifibrotic effects.
research PRX102 Participates in Root Hairs Tip Growth of Rice
This study found that PRX102, a peroxidase with a unique polar localization pattern, plays a role in root hair growth by aiding the transport of materials to the tips of growing root hairs.
research 42752 Evaluation of Eyebrow and Eyelash Regrowth and Patient Satisfaction in the Phase 3 THRIVE-AA1 Trial with CTP-543 (Deuruxolitinib) in Adult Patients with Moderate to Severe Alopecia Areata
CTP-543 significantly improved eyebrow and eyelash regrowth and patient satisfaction in adults with alopecia areata.
research Ontogeny of enhancing factor in mouse intestines and skin
Enhancing Factor is found in growing tissues like young mouse intestines and skin but not in adults.
research Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth
This study found that non-pigmented hair follicles have significantly lower expression of nucleotide excision repair genes, which may be associated with reduced melanin production capacity in these follicles.
research 198 Reliable and interpretable segmentation for remote assessment of atopic dermatitis severity using digital images
This study reports that improvements to the EczemaNet pipeline, incorporating pixel-level segmentation and data augmentation, enhanced the reliability and interpretability of assessing atopic dermatitis severity from digital images.
research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration
This study suggests that epithelial-derived Pop-Up Keratinocytes (ePUKs) may be a promising cell source for regenerative medicine due to their specific phenotypic traits and their influence on wound healing.
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
This study found that the PP2A-B55α regulatory subunit is crucial for ectodermal development in mice, with knockout embryos displaying severe neural and epidermal defects and failing to survive to birth.
research Evidence for multiple, developmentally regulated isoforms of Ptprq on hair cells of the inner ear
This study suggests that Ptprq in the hair bundles may exist as multiple isoforms that are differentially expressed throughout development and affect the organization of stereocilia in the chick inner ear.
research Safety and Efficacy of Mesotherapy with Placenta Polypeptide Injection for Moderate-to-Severe Sensitive Skin: A Multicenter, Randomized, Controlled Trial
This study found that mesotherapy with placenta polypeptide injection significantly reduced skin inflammation and improved aesthetic outcomes in adults with moderate-to-severe sensitive skin, without increasing adverse events compared to controls.
research The Autoimmune Regulator (AIRE), Which Is Defective in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients, Is Expressed in Human Epidermal and Follicular Keratinocytes and Associates With the Intermediate Filament Protein Cytokeratin 17
This study found that AIRE, a usually nuclear protein, is expressed in the cytoplasm of human epidermal and follicular keratinocytes and associates with the intermediate filament protein cytokeratin 17, potentially impacting ectodermal abnormalities in APECED syndrome.
research Hippocampal 3α,5α-THP may alter depressive behavior of pregnant and lactating rats
Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.
research O04 HPV8 E6 leads to Lrig1+ keratinocyte stem cell expansion
This study found that the E6 gene, but not E7, was responsible for HPV8-induced expansion of keratinocyte stem cells in hair follicle junctional zones in mice.
research P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss
This study found that lineage-restricted loss of p63 in murine thymic epithelial cells resulted in severe thymic hypoplasia and absence of hair follicles, indicating p63's critical role in thymic and hair follicle development.
research Stability Studies on L-Ascorbic Acid dl-α-Tocopherol Phosphoric Acid Diester Potassium Salt (EPC-K)
In this study, EPC-K, a compound with antioxidant and moisturizing effects, was found to decompose significantly under certain conditions, impacting its stability in quasi drug hair-growing products.
research Effects of in vivo-administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on receptor binding of epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster.
This study found that TCDD significantly reduced EGF receptor binding in various animal models, linked to toxic symptoms like weight loss and developmental delays, with receptor phosphorylation persisting several days.
research Mapping of cis-acting expression quantitative trait loci in human scalp hair follicles
This study identified 374 eQTLs in scalp hair follicles associated with genes involved in metabolic, mitotic, immune processes, and responses to steroid hormones, contributing insights into genetic variation and hair traits.
research Preliminary investigations of rat skin after topical application of optical clearing agent
This study found that while short-term use of PEG-400 and Thiazone affected rat skin structure, the changes were reversible with no long-term effects observed.
research Pseudallescheria boydii infection associated with IgG4-related disease
This report identifies a novel splice-site variant in the LAMB3 gene linked to junctional epidermolysis bullosa, emphasizing the need for gene sequencing in diagnosing the disease.
research 464 Phenotypic heterogeneity of epidermolysis bullosa associated with the recurrent pathogenic variant p.(Arg2000Trp) in plectin
This study found that alopecia areata patients have higher odds of certain comorbidities like ulcerative colitis and vitiligo, while showing lower odds for conditions like hypertension and type 2 diabetes compared to healthy controls.
research p63 expression in normal skin and usual cutaneous carcinomas
This study suggests that p63 is consistently expressed in the basal cells of the skin and may influence differentiation and the development of common skin carcinomas.
research A novel calmodulin‐interacting Domain of Unknown Function 506 protein represses root hair elongation in Arabidopsis
In this study, the authors reported that AtRXR3, a phosphorus-inducible DUF506 protein, modulates root hair growth under phosphorus stress by interacting with calmodulin and influencing calcium oscillations.