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570-600 / 1000+ resultsresearch Scaffold-based developmental tissue engineering strategies for ectodermal organ regeneration
This review discusses recent advances in developmental tissue engineering for regenerating ectodermal appendages like teeth and glands, emphasizing biomaterial selection and cell culture strategies, but reports no new experimental results.
research Generalized pustular toxic erythema: pathogenetic relationship between pustule and epidermal appendage (hair follicle or sweat duct)
In this study, seven patients with generalized toxic erythema developed sterile pustules localized to hair follicles or sweat ducts, with most having a history of medication, solvent exposure, or infection.
research Risk of erythrocytosis in transgender individuals undergoing testosterone therapy: a systematic review
In this systematic review, an increase in hemoglobin and hematocrit was associated with testosterone therapy, especially within the first year, and factors like serum testosterone levels and therapy specifics were linked to erythrocytosis development, highlighting the need for further research to guide clinical practice.
research The Free Communications of the Eighth Clinical Congress (Virtual) of the Gulf Chapter of the American Association of Clinical Endocrinologists; November 5–7, 2020
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research Coexistence of alopecia areata and fixed drug eruption: An uncommon isotopic phenomenon?
This case study reports a rare instance of both alopecia areata and fixed drug eruption occurring in the same area on a 40-year-old man's beard, triggered by oral paracetamol, highlighting potential shared pathogenic pathways and the isotopic phenomenon.
research 612 Targeted hair follicle delivery of hydrophilic molecules
This study found that a new formulation using short chain esters and ethanol can selectively deliver hydrogen peroxide to hair follicles during epilation, causing follicular damage without affecting epidermal keratinocytes.
research Taiwanese Dermatological Association consensus for the prevention and management of epidermal growth factor receptor tyrosine kinase inhibitor-related skin toxicities
This report presents the Taiwanese Dermatological Association's 2016 consensus on defining and managing skin toxicities from EGFR-TKI treatments, providing comprehensive guidelines for clinicians in Taiwan.
research TSPO ligand etifoxine attenuates LPS-induced cognitive dysfunction in mice
This study found that etifoxine pretreatment reduced neuroinflammation and improved cognitive function in LPS-induced neuroinflammation in mice, potentially through increased neurosteroid synthesis and reduced apoptosis.
research 599 Amelioration of symptoms of dry and eczema-prone skin by an oil-in-water emulsion containing a combination of a zingiber officinale root extract and cbd with antioxidative and anti-inflammatory activity in vitro
In this study, a new emulsion containing CBD and ginger root extract significantly reduced symptoms of dry and eczema-prone skin, such as erythema and itching, in a clinical trial.
research Ganoderma lucidum ethanolic extract for the treatment of androgenic alopecia in rats with testosterone-induced Baldness.
This study found that an ethanolic extract of Ganoderma lucidum, especially at 15mg/kg, may promote hair growth in a rat model of testosterone-induced alopecia, showing effects comparable to minoxidil.
research Detection of cortisol, estradiol, and testosterone in archaeological human hair from the Dakhleh Oasis, Egypt
This study demonstrated that cortisol, estradiol, and testosterone are preserved in archaeological human hair, allowing for the analysis of ancient stress and reproductive hormone patterns.
research METABOLIC DISOEDEKS AND HAIE GEOWTH
Hair can indicate early signs of metabolic disorders, with issues like protein deficiency stopping hair growth.
research Eclipta alba, An Antioxidant-Rich Memory Enhancer: In-Silicoand In-Vivo Evidence with Specific Insight into Alzheimer’s Disease
In this study, researchers identified several active metabolites in Eclipta alba, demonstrated strong interaction with Alzheimer's disease proteins, and found that 28 days of treatment improved memory without significant toxicity in rats, suggesting potential pathways for treating Alzheimer's.
research Signs of Potential Androgen Excess Across the Lifespan in a US-based Digital Cohort Study
This study found that signs of potential adverse events varied based on demographic and health factors in a large cohort, suggesting the need for more inclusive evaluations to better understand these differences at a population level.
research Safety profile of CAP7.1 obtained during Phase I Trial in adult patients with refractory malignancies
In this study, the safety profile of the prodrug CAP7.1 was found to be similar to other topoisomerase inhibitors, with myelosuppression as the main dose-limiting toxicity.
research Hair Growth–Promoting Activity of Flavone-Rich Fractions Derived from Eremochloa ophiuroides extracts
In this study, Eremochloa ophiuroides-derived fractions were found to significantly promote hair regrowth in a mouse model, demonstrating effects comparable to minoxidil and suggesting potential as natural hair growth agents through modulation of follicular activation markers and growth-regulatory factors.
research Case of intractable ophiasis type of alopecia areata presumably improved by fexofenadine
This letter reports on a case of intractable ophiasis-type alopecia areata that was presumably improved by fexofenadine, but no new clinical results are presented.
research Lentinula edodes (Shiitake) extract as a vitamin D receptor activator to enhance skin adaptogenic responses
This study suggests that a Lentinula edodes extract can improve skin barrier function, hydration, and sebum regulation, possibly by modulating vitamin D pathways, in individuals with oily and acne-prone skin.
research Alopecia areata induzida após síndrome DRESS com rápida resolução
This report describes a 17-year-old woman who experienced severe anagen effluvium after DRESS syndrome but achieved full recovery in two months with topical minoxidil.
research Modeling of ionizing radiation induced hair follicle regenerative dynamics
This study developed a mathematical model to explore hair follicle regeneration mechanisms, showing that low spontaneous apoptosis rates help regenerate hair follicles after ionizing radiation, while high rates lead to degeneration during the catagen phase.
research The influence of long-term treatment with cyproterone acetate or a cyproterone acetate-ethinyl oestradiol combination on androgen levels in blood of hirsute women
This study found that both cyproterone acetate alone and combined with ethinyl oestradiol reduced androgen levels and slightly increased SHBG binding in women with hirsutism, but showed no difference in hair regrowth rate between the treatments.
research Chinese Herbal Medicine, Guilu Erxian Glue, as Alternative Medicine for Adverse Side Effects of Chemotherapy in Doxorubicin-Treated Cell and Mouse Models
This study found that Guilu Erxian Glue significantly alleviates various doxorubicin-induced side effects in mice, enhancing exercise capacity and reducing oxidative stress and inflammation.
research Inhibition of 5α-Reductase, IL-6 Secretion, and Oxidation Process of Equisetum debile Roxb. ex Vaucher Extract as Functional Food and Nutraceuticals Ingredients
This study suggests that ethyl acetate extract of Equisetum debile may be effective for functional food and nutraceutical use due to its strong 5α-reductase, IL-6 inhibition, and lipid peroxidation activities without cytotoxic effects.
research Eph Receptors and Ephrins: Therapeutic Opportunities
This review discusses the roles of Eph receptors and ephrins in various diseases, highlighting their potential as therapeutic targets, but it presents no new research findings.
research 홍삼가수분해추출물(GS-E3D)의 항산화 및 양모 효과
This study found that pectin lyase-modified red ginseng extract (GS-E3D) may promote hair growth by enhancing antioxidant and anti-inflammatory effects, proliferating hair dermal papilla cells, and inhibiting 5α-reductase activity.
research Formulation and evaluation of self-nanoemulsifying drug delivery system for improved oral delivery of exemestane hydrochloride
This study explored the development of a self nanoemulsifying drug delivery system to enhance the solubility and oral bioavailability of exemestane HCl for breast cancer therapy.
research Clinical and dermoscopic evaluation of red light emitting diodes with beta-carotene versus red light emitting diodes alone in treatment of photoaging
This study found that combining red light therapy with oral beta-carotene significantly improved photoaging treatment outcomes compared to red light therapy alone, with Group A showing a 56.12% reduction in photoaging scores over 12 weeks versus 44.78% in Group B.
research Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor
This study found that mitochondrial oxidative phosphorylation in epithelial cells is necessary for proper enamel formation and odontoblast differentiation in developing incisor teeth in K320E-Twinkle Epi mice.
research Human Essential Fatty Acid Deficiency
In this case report, applying linoleic acid topically reversed essential fatty acid deficiency and related skin symptoms in a patient receiving long-term fat-free intravenous nutrition.