Risk of Erythrocytosis in Transgender Individuals Undergoing Testosterone Therapy: A Systematic Review

    July 2024 in “ Minerva Endocrinology ”
    Alberto Scala, Andrea Graziani, Fabrizio Vianello … Gender Incongruence Interdisciplinary Group
    Studysummary In this systematic review, an increase in hemoglobin and hematocrit was associated with testosterone therapy, especially within the first year, and factors like serum testosterone levels and therapy specifics were linked to erythrocytosis development, highlighting the need for further research to guide clinical practice.
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    Research cited in this study 3

    1. Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline The Journal of Clinical Endocrinology & Metabolism · 2017
    2. Cross-Sex Hormone Therapy in Trans Persons Is Safe and Effective at Short-Term Follow-Up: Results from the European Network for the Investigation of Gender Incongruence The Journal of Sexual Medicine · 2014
    3. Effects of Intramuscular Testosterone Undecanoate on Body Composition and Bone Mineral Density in Female-to-Male Transsexuals ˜The œjournal of sexual medicine · 2010

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