Taiwanese Dermatological Association Consensus for the Prevention and Management of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor-Related Skin Toxicities

    Chia‐Yu Chu, Kuan‐Yu Chen, John Wen‐Cheng Chang, Yufeng Wei, Chih‐Hung Lee, Weiming Wang
    Studysummary This report presents the Taiwanese Dermatological Association's 2016 consensus on defining and managing skin toxicities from EGFR-TKI treatments, providing comprehensive guidelines for clinicians in Taiwan.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The 2016 consensus of the Taiwanese Dermatological Association (TDA) provided comprehensive guidelines for preventing and managing skin toxicities caused by epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). The guidelines addressed six major skin toxicities, including acneiform rash, xeroderma, pruritus, paronychia, stomatitis, mucositis, and hair changes, with specific definitions, onset times, grading, care suggestions, and treatment algorithms for each. The recommendations aimed to improve the quality of life for patients undergoing EGFR-TKI treatment by preventing treatment interruptions due to severe skin toxicities. The consensus was supported by 100% of the 15 experts in attendance.
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