October 2025 in “Burns & Trauma” This review highlights recent advancements in engineered probiotics for wound healing, reporting that genetically engineered strains of Lactobacillus reuteri and Lactococcus cremoris have shown promise in promoting faster wound healing in pre-clinical and clinical settings, particularly for diabetic foot ulcers.
1 citations
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December 2023 in “npj biofilms and microbiomes” This review highlights the potential of genetically or metabolically engineered live biotherapeutic products (eLBPs) for skin repair and disease treatment but emphasizes that translating these innovations into practical clinical applications remains challenging, requiring further research and development.
6 citations
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July 2021 in “Microbial biotechnology” This study found that combining LED yellow light with an engineered strain expressing CXCL12 improved wound healing and reduced inflammation in a mouse model of scald wounds.
April 2026 in “International Journal of Drug Delivery Technology” This study found that Lactobacillus acidophilus cell-free supernatant caused significant cytotoxicity, reduced migratory ability, and induced apoptosis in cervical cancer cell lines, suggesting its potential as a non-toxic adjunct therapy for cervical cancer.
51 citations
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January 2024 in “Burns & Trauma” This review summarizes the therapeutic potential and development of engineered extracellular vesicles for tissue repair and regenerative medicine, reporting no new clinical findings.
November 2025 in “Advanced Healthcare Materials” This review explores advancements in bioprinting technologies for developing in vitro skin models that replicate immune-mediated skin diseases, highlighting their potential to reduce animal testing and enhance research and product testing capabilities in dermatology.
100 citations
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August 2022 in “Microbial Cell Factories” This review discusses the interactions between skin microbiota and human skin health, examining how imbalances may contribute to skin diseases, and reports no new clinical results.
114 citations
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February 2023 in “International Journal of Molecular Sciences” This review discusses the relationship between skin microbiome changes and conditions such as ageing and skin disease, emphasizing the need for further research, but reports no new findings.
8 citations
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July 2025 in “Gels” This review discusses how functionalized hydrogels can modulate the microbiome to aid tissue regeneration and infection control, highlighting their potential to deliver therapeutic agents effectively and support beneficial immune responses.
February 2026 in “Middle European Scientific Bulletin” In this study, researchers explored the formation of the skin's epidermal barrier, its interplay with skin microbiota, and the role of skin appendages, suggesting that probiotics might offer promising avenues for treating scalp diseases, particularly those affecting hair loss.
January 2025 in “Dermatology Research and Practice” This study examines how skin microbiota and the gut-skin axis affect acne development, aiming to reveal mechanisms that could inform future treatment strategies for acne and other inflammatory skin conditions.
1 citations
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July 2023 in “Frontiers in Immunology” This review highlights the role of chronic stress, oxidative stress, and immune processes in the development of Hashimoto’s thyroiditis and polycystic ovary syndrome, emphasizing the potential of antioxidants in their treatment based on the existing literature.
This paper highlights the role of the skin microbiome in influencing skin and hair conditions, suggesting that understanding these microbial communities could aid in developing new probiotic or antibiotic treatments for disorders like alopecia and skin diseases.
8 citations
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February 2025 in “Cell Systems” This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.
45 citations
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November 2024 in “International Journal of Molecular Sciences” This review discusses how various nutrients, such as flavonoids, probiotics, and omega-3 fatty acids, may support brain health by targeting stress-related pathways, potentially offering protective effects against neurodegenerative and psychiatric disorders through their roles in oxidative stress reduction and neuroinflammation regulation.
26 citations
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September 2023 in “Bioengineered” This review article discusses recent progress in the extraction and potential health benefits of oligosaccharides from brown seaweeds, especially focusing on their antimicrobial, anti-inflammatory, and prebiotic properties, and possible applications in managing metabolic syndrome.
2 citations
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January 2026 in “Frontiers in Endocrinology” This review discusses the impaired functionality of regulatory T cells in the pancreas during the development of Type 1 diabetes, highlighting their role in disease pathogenesis, potential of Treg-based therapies, and challenges in clinical applications.
April 2026 in “Regenerative Medicine” This source does not report specific results but compiles information on recent advancements in Advanced Therapy Medicinal Products and regenerative medicine from non-academic sources as of March 2026.
194 citations
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October 2018 in “Microbiome” This study examined recent findings on the role of host-microbiome interactions in acne, highlighting that the skin's microbiome composition differs between acne-affected and healthy individuals and discussing emerging microbiome-based treatments.
5 citations
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November 2025 in “Cells” This review summarizes the roles of various cells and signaling pathways in skin wound healing, highlights deviations leading to pathological outcomes like chronic wounds, and evaluates cutting-edge approaches such as biomaterials and precision medicine to improve healing and intervention strategies.
2 citations
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November 2025 in “International Journal of Molecular Sciences” This review highlights that the skin microbiota plays a crucial role in wound healing, with beneficial microorganisms aiding tissue repair and opportunistic pathogens hindering it, potentially guiding future microbiome-targeted therapies.
This review summarizes the composition, bioactive functions, and potential industrial applications of rice bran polysaccharides, focusing on how extraction methods and modifications impact their biological activities.
August 2023 in “Fermentation” This review discusses the potential of metabolic engineering to enable sustainable industrial-scale production of L-aspartate and its derivatives, detailing current microbial production progress, limiting factors, and future prospects with emerging technologies in synthetic biology.
August 2025 in “International Journal for Research in Applied Science and Engineering Technology” In this study, rice water was reviewed as a cosmetic ingredient, highlighting its safety, stability, and possible benefits such as anti-inflammatory and anti-aging effects, as well as improvements in hair growth and skin hydration.
This review highlights that surface mechanical regulation can program macrophage behavior through specific mechanical cues on material surfaces, potentially advancing immunotherapies and regenerative medicine by enabling precise control over macrophage functions.
1 citations
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January 2026 in “Frontiers in Bioengineering and Biotechnology” This review discusses various nanocarriers for gene and genome editing therapies, highlighting that ionizable lipid nanoparticles show advanced delivery performance, while emerging polymer-based and exosome-inspired carriers are rapidly advancing for targeted applications.
May 2024 in “International journal of nanomedicine” This review highlights the potential of extracellular vesicles derived from medicinal plants as therapeutics for diseases such as cancer and inflammation, suggesting they may enhance the clinical use of herbal preparations, despite the challenges posed by extract complexity and individual variability.
13 citations
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February 2017 in “Science” Turning scar-forming cells into fat cells can reduce scarring.
2 citations
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June 2026 in “Frontiers in Science” This review examines the potential of regulatory T cell-based therapies to transform treatment across various medical specialties by promoting immune tolerance and tissue repair, but it reports no new clinical results.
24 citations
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January 2019 in “Science China Life Sciences” Chitosan/LiCl composite scaffolds help heal deep skin wounds better.