Advances in the Human Skin Microbiota and Its Roles in Cutaneous Diseases

The review discussed the significant role of skin microbiota in human health and its impact on skin diseases such as acne, psoriasis, and atopic dermatitis. It highlighted the influence of skin microbiota on the skin's defense against pathogens and the consequences of microbiota imbalance, which contributed to these diseases. Advances in sequencing technologies identified specific bacterial strains that could either contribute to or protect against these conditions. The review suggested that future treatments should consider microbiota modulation, including probiotics and microbiota transplantation, as alternatives to traditional methods like antibiotics. It also explored prevention, diagnosis, and treatment strategies, including healthy diets, lifestyles, and the potential of synthetic biology to modulate skin microbiota. Understanding the balance between skin and microbiota was deemed essential for maintaining healthy skin and developing new therapeutic strategies.