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Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Aromatase gene variation may increase female hair loss risk.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

PCOS is a common hormonal disorder in women, treated with lifestyle changes and medications like hormonal contraceptives and metformin.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.