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Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

EtG in hair can help detect alcohol use but may be inaccurate in people with certain health conditions.

Using 5-aminolevulinic acid photodynamic therapy for hair loss didn't increase hair growth but slightly reduced scalp oiliness, and it was safe with mild side effects.

Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.

High YKL-40 levels predict early hair loss and hidden metabolic issues.

Cirrhosis affects quality of life with various symptoms, requiring a holistic, multidisciplinary approach for management.

Chromosomal differences affect how muscle cells respond to testosterone.

Finasteride treats hair loss and reduces prostate cancer risk.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Aminoguanidine increases a specific growth signal in stored hair grafts, which may help them survive better after being transplanted.

Aminoguanidine increases VEGF in stored hair micrografts, potentially improving their viability after transplant.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.

Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Obesity is linked to various skin disorders, which can help with early diagnosis and prevention of long-term health issues.

The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.