Two Transgender Men Receiving Subdermal Testosterone Pellets for Gender Affirmation

The document reports on two cases of transgender men using subdermal testosterone pellets for gender affirmation. Patient 1, a 47-year-old, experienced wide fluctuations in testosterone levels with pellets and returned to injections. Patient 2, a 20-year-old, found pellets to be a suitable alternative after struggling with gel and injections. Both patients tolerated the pellets well without significant adverse effects. The study suggests that testosterone pellets could be a viable long-acting option but stresses the need for larger, controlled studies to determine optimal dosing and to monitor for risks like erythrocytosis.