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This study found that human hair follicles can function like a peripheral hypothalamic-pituitary-adrenal axis, synthesizing cortisol in response to corticotropin-releasing hormone and adrenocorticotropic hormone stimulation.

This article discusses how nutritional and environmental factors, along with antioxidant supplementation, may improve hair growth by mitigating the effects of androgens and reports no new clinical results.

This review discusses the role of various hormones in diffuse hair loss and emphasizes the need for further research to clarify their complex interactions and potential therapeutic implications, but reports no new clinical results.

A rare pancreatic tumor caused a woman's male-like features, treated successfully with surgery and medication.

This study found that normal human epidermis expresses TSH and may be an indirect target of TSH signaling, with expression regulated by endocrine controls of the hypothalamic-pituitary-thyroid axis.

In a controlled study, researchers observed that lambs exposed to colder temperatures had increased wool growth, thicker skin, altered physiological traits, and activated specific molecular pathways, highlighting potential targets for enhancing cold tolerance, welfare, and productivity in sheep breeds.

This review explores the potential (neuro-)endocrine influences on hair follicle epithelial stem cell biology and emphasizes the need for more systematic research, but it provides no new empirical results.

In this randomized controlled trial, combining cinnamon and inositol led to significant improvements in metabolic and hormonal parameters, such as reduced LH, testosterone, fasting glucose, and ovarian ultrasound scores, in overweight women with PCOS, indicating superior benefits over either supplement alone.

In this study, researchers found that Hashimoto's thyroiditis patients, despite being in euthyroid status, experienced more severe extrathyroidal symptoms compared to healthy controls, and elevated thyroid antibodies were linked to lower health-related quality of life and increased inflammation.

The skin is essential for protection, temperature control, and immune defense.

This study suggests that patients with STSD show a different pattern in androgen activation compared to healthy controls, potentially due to increased 5α-reductase activity and absent prepubertal serum DHEA surge.

In this study, the combination of camouflage and psychotherapy significantly improved quality of life for vitiligo patients and potentially modulated psycho-neuro-endocrine-immune interactions.

This review summarizes recent studies on metformin for polycystic ovary syndrome, reporting its beneficial effects on endocrine, metabolic, and reproductive outcomes, but highlights ongoing debate about its mechanisms.

This study concluded that COVID-19 is a multisystem disease with both pulmonary and extrapulmonary manifestations, underscoring the importance of considering these symptoms for early diagnosis and infection control.

This study found that men taking 1 mg/day of finasteride had significantly reduced sperm production and morphology but similar hormonal, sexual, and psychological profiles compared to controls, suggesting finasteride affects semen quality without altering other physiological functions.

This case report describes the first known instance of a patient with myotonic dystrophy presenting with type I diabetes, Hashimoto’s thyroiditis, and follicular variant papillary thyroid cancer, suggesting a potential link between these conditions.

This review covers various treatments for managing PCOS symptoms and infertility, noting that aromatase inhibitors may be as or more effective than clomiphene citrate for ovulation induction but reports no new clinical results.

Women with thinning hair have thinner hair strands than women without hair loss.

Higher thyroid hormone levels may be linked to certain types of polycystic ovary syndrome.

This abstract reviews the characteristics and health risks associated with polycystic ovary syndrome and does not report new findings, highlighting the syndrome's multifactorial nature.

Diffuse alopecia in women may be related to androgens and iron deficiency, and basic hormone and nutrient screening is useful.

In this study, genetic factors associated with hirsutism were identified, suggesting that both androgen-dependent and independent mechanisms may contribute to excessive hair growth in women.

In this study, researchers observed that treatment with Agaricus subrufescens ethanolic extract improved blood glucose, testosterone levels, and menstrual irregularity in rat models of letrozole-induced Polycystic Ovarian Syndrome, also noting a decrease in elevated liver and ovary weights, suggesting protective effects on renal function.

This study suggests that the protease HAT-L4 plays a significant role in maintaining epidermal barrier function to prevent body fluid loss, as its absence in mice led to increased fluid loss and higher mortality.

This article reviews the complex pathophysiology of polycystic ovary syndrome, highlighting how genetic, hormonal, and environmental factors contribute to its diverse symptoms, and reports no new results.

This review found that women with idiopathic hirsutism may have increased 5α-reductase activity, as indicated by elevated levels of a dihydrotestosterone-reduced metabolite, but more research is needed to confirm its clinical relevance as a biomarker.

This study found that men with early-onset androgenetic alopecia who also met criteria for the male PCOS-equivalent may have impaired gonadal steroidogenesis, suggesting increased risk of future gonadal dysfunction.

Proximal hair cortisol is a reliable tool for diagnosing Cushing's Syndrome.

SFRP-4 might be an early indicator of diabetes and hypertension in men with androgenic alopecia.