Polycystic Ovary Syndrome and Infertility: An Update

    July 2021 in “ International journal of adolescent medicine and health ”
    Mehrukh Zehravi, Mudasir Maqbool, Irfat Ara
    TLDR New treatments for PCOS are improving fertility and managing symptoms better.
    Polycystic ovarian syndrome (PCOS) is a prevalent endocrine disorder characterized by symptoms such as hyperandrogenism, irregular menstrual cycles, and insulin resistance, which can lead to infertility, insulin resistance, and type 2 diabetes. Treatment goals include reducing body weight and insulin levels, restoring fertility, controlling hair growth, maintaining regular menstrual cycles, and preventing complications. Metformin and thiazolidinediones are common treatments for insulin resistance in PCOS, with newer therapies like statins and incretins targeting metabolic aspects of the condition. Alternative treatments like vitamin D, acarbose, and myoinositol have also shown effectiveness. For infertility, clomiphene citrate has been the standard for ovulation induction, but aromatase inhibitors are now providing comparable or superior results. Advanced treatments include protocols using gonadotropins, gonadotropin-releasing hormone antagonists, ovarian drilling, and assisted reproductive technologies with in vitro oocyte maturation, reflecting significant therapeutic advancements in managing PCOS-related infertility.
    Discuss this study in the Community →

    Research cited in this study

    5 / 5 results

    Related Community Posts Join

    6 / 12 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Bryan Johnson just dropped his anti hair loss formula

      in Treatment  339 upvotes 10 months ago
      Bryan Johnson shared his hair loss treatment, which mainly relies on minoxidil and finasteride. Some users are skeptical of his results, while others appreciate his efforts in anti-aging and hair loss research.

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  53 upvotes 1 year ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community having hair loss as a teen SUCKS. A LOT.

      in Female  12 upvotes 2 years ago
      A teenage girl who has been diagnosed with ADA and is struggling with hair loss, which has caused her to lose confidence. She is looking for recommendations on treatments such as finasteride or Minoxidil, and lifestyle advice including vitamins and other supplements that might help with the issue.

      community My scalp punch biopsy results🤔?

      in Female  9 upvotes 1 year ago
      Female using Rogaine foam for hair loss had scalp punch biopsy, diagnosed with Androgenetic Alopecia (AGA). Doctor recommended starting Spironolactone 50mg.

    Related Research

    3 / 3 results