research The Molecular Anatomy of Cashmere Goat Hair Follicle During Cytodifferentiation Stage
Understanding hair follicle development can help improve cashmere quality.
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research Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells
Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
research CCN2 Modulates Hair Follicle Cycling in Mice
The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
research Hair Follicle Stem Cells: Walking the Maze
Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
research Detecting the Mechanism Behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus Nippon) Dermal Papilla Cells to Three-Dimensional Pattern
The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.
research Skin Tissue Engineering: Potential of Stem Cell Biology and Skin Morphogenesis
Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
research Regulation of VDR by ΔNp63α Is Associated with Inhibition of Cell Invasion
ΔNp63α helps control a protein that stops cancer cells from spreading.
research Caspases in Life and Death: Their Role in Head Formation
Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.
research LGR5 Is a Conserved Marker of Hair Follicle Stem Cells in Multiple Species and Is Present Early and Throughout Follicle Morphogenesis
LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
research Functional Hair Follicle Regeneration: An Updated Review
Hair follicle regeneration possible, more research needed.
research IGF1 and BM-MSC Incorporating Collagen-Chitosan Scaffolds Promote Wound Healing and Hair Follicle Regeneration
Adding insulin-like growth factor 1 and bone marrow-derived stem cells to a collagen-chitosan scaffold helps wounds heal faster and regrows hair follicles.
research Stem Cell Therapy and Hair Loss: Present Evidence and Future Perspectives
Stem cell therapy shows promise for hair loss treatment, but more research is needed to confirm its effectiveness.
research α3β1-Integrin Regulates Hair Follicle But Not Interfollicular Morphogenesis in Adult Epidermis
α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
research Stem-Cell Therapy in Dermatology: Challenges and Opportunities
Stem-cell therapy shows promise for skin conditions but needs more research.
research Future Horizons in Hair Restoration
New cell-based therapies may improve hair loss treatments in the future.
research In This Issue
The studies identified key factors and potential treatments for skin and hair disorders.
research Hair Disorders
The document explains different hair loss types and treatments, emphasizing diagnosis through examination and tests, and specific treatments for each condition.
research Engineering the Niche for Hair Regeneration: A Critical Review
Further research is needed to improve hair regeneration using stem cells and nanomaterials.
research Dendrobium Officinale Polysaccharide Promotes Angiogenesis, Follicle Regeneration, and Hair Growth Through Activation of the WNT Signaling Pathway
Dendrobium officinale polysaccharide helps hair growth by activating the WNT signaling pathway.
research Thyroid Autoimmunity in Patients with Skin Disorders
People with alopecia areata often have thyroid autoimmunity.
research 3D Bioprinting of Prefabricated Artificial Skin with Multicomponent Hydrogel for Skin and Hair Follicle Regeneration
This study investigates the use of 3D bioprinting with multicomponent hydrogels, specifically a combination of gelatin methacrylate (GelMA) and hyaluronic acid methacrylate (HAMA), to create artificial skin capable of regenerating skin and hair follicles. The research involved using epidermal stem cells (Epi-SCs) and skin-derived precursors (SKPs) within the hydrogel, which demonstrated excellent printability, biocompatibility, and mechanical properties. When tested in vivo on mice, the artificial skin facilitated complete wound healing and regeneration of functional tissues, including hair follicles, within 4 weeks. This approach shows significant potential for clinical applications in skin and hair follicle regeneration, although challenges remain in scaling up stem cell cultures and verifying efficacy with human cells.
research Engineering the Future of Hair Follicle Regeneration and Delivery
Hair follicle regeneration and delivery is complex due to many molecular and cellular factors.
research Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome
Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.
research Hair Growth Activity of Seeds and Fruit Pulp of Eugenia Jambolana (Jamun)
Jamun fruit pulp extract is better at promoting hair growth than seed extract.
research The Melanocyte Photosensory System in Human Skin
Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.
research Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-Associated Protein Genes on Chromosome 21q22.1
Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.
research Androgen Actions on the Human Hair Follicle: Perspectives
Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.
research Transcriptome Analysis Reveals the Genetic Basis Underlying the Development of Skin Appendages and Immunity in Hedgehog (Atelerix Albiventris)
The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
research Stem Cell: Current and Future State
Stem cells show promise for hair loss treatment, but no effective product for hair regeneration has been developed yet.
research Genetic and Molecular Aspects of Androgenetic Alopecia
Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.