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450-480 / 1000+ resultsresearch Multipotent Nestin-Positive Stem Cells Reside in the Stroma of Human Eccrine and Apocrine Sweat Glands and Can Be Propagated Robustly In Vitro
Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
research Investigation of hub genes and immune infiltration in androgenetic alopecia using bioinformatics analysis
research [Genetic dissection of retinoic acid function in epidermis physiology].
Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.
![Promotion of hair follicle development and trichogenesis by Wnt-10b in cultured embryonic skin and in reconstituted skin](/images/research/a5aadd7d-7b58-4a0d-b5d8-da3f6eeede1b/small/23238.jpg)
research Promotion of hair follicle development and trichogenesis by Wnt-10b in cultured embryonic skin and in reconstituted skin
Wnt-10b is important for starting hair growth and developing hair follicles.
![Bone vs. fat: Embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts](/images/research/112749e6-9434-443c-be2f-13d61b56e8b8/small/26120.jpg)
research Bone vs. fat: Embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
![Apoptosis in human skin development: Morphogenesis, periderm, and stem cells](/images/research/5aac88a3-7d73-4c20-803a-7931c092bb48/small/36575.jpg)
research Apoptosis in human skin development: Morphogenesis, periderm, and stem cells
Apoptosis is essential for human skin development and forming a functional epidermis.
![Development and homeostasis of the sebaceous gland](/images/research/727feb97-4c91-4037-b57c-0f54dd71592d/small/14639.jpg)
research Development and homeostasis of the sebaceous gland
The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
research Edar Signaling in the Control of Hair Follicle Development
Edar signaling is crucial for proper hair follicle development and function.
![Small molecules and small molecule drugs in regenerative medicine](/images/research/13ecad17-1bc7-4c34-8e5d-79e2df07a152/small/14319.jpg)
research Small molecules and small molecule drugs in regenerative medicine
Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
![Newly born mesenchymal cells disperse through a rapid mechanosensitive migration](/images/research/8512c7f3-abac-42c7-8fa5-30211428981c/small/32914.jpg)
research Newly born mesenchymal cells disperse through a rapid mechanosensitive migration
Newly born mesenchymal cells quickly spread out in response to tissue tension during early development.
![KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin](/images/research/74da5aaf-c1cb-4308-b4ce-7cd976c43a37/small/33032.jpg)
research KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin
EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
![Parathyroid Hormone Hormone-Related Protein and the PTH Receptor Regulate Angiogenesis of the Skin](/images/research/5996c793-a28e-4fc6-ace5-c0f86ac1b1c9/small/15193.jpg)
research Parathyroid Hormone Hormone-Related Protein and the PTH Receptor Regulate Angiogenesis of the Skin
PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.
![p53‐dependent transcriptional regulation of EDA2R and its involvement in chemotherapy‐induced hair loss](/images/research/3fe26dd1-cdbe-414d-a03e-26165ea49b13/small/26487.jpg)
research p53‐dependent transcriptional regulation of EDA2R and its involvement in chemotherapy‐induced hair loss
The study concludes that the EDA2R gene is activated by p53 during chemotherapy but is not necessary for chemotherapy-induced hair loss.
![Hair organ regeneration via the bioengineered hair follicular unit transplantation](/images/research/1c2a4e6f-af0b-4946-9546-c7bc30e981a8/small/19840.jpg)
research Hair organ regeneration via the bioengineered hair follicular unit transplantation
Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
![Transformation of amnion epithelium into skin and hair follicles](/images/research/96ba1aee-b054-422c-a226-a9908895708d/small/29544.jpg)
research Transformation of amnion epithelium into skin and hair follicles
Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.
![Fondation René Touraine](/images/research/dba1a9e9-36fd-4b67-97b3-56346d9d3fab/small/18969.jpg)
research Fondation René Touraine
The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
![Impact of adipose-derived stem cells on engineering hair follicle germ-like tissue grafts for hair regenerative medicine](/images/research/c610d209-0b66-4f34-933a-0f408a52e785/small/17203.jpg)
research Impact of adipose-derived stem cells on engineering hair follicle germ-like tissue grafts for hair regenerative medicine
Adding human fat-derived stem cells to hair follicle grafts greatly increases hair growth.
research STAT3 Partly Inhibits Cell Proliferation via Direct Negative Regulation of FST Gene Expression
The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.
![The Organizer and Beyond](/images/research/3eb0b6ff-fed3-4b53-ae1d-6dd3594c834d/small/35691.jpg)
research The Organizer and Beyond
Cells from certain embryo parts can induce head formation in another embryo, involving complex signaling pathways.
![Thymosin β4 Identified by Transcriptomic Analysis from HF Anagen to Telogen Promotes Proliferation of SHF-DPCs in Albas Cashmere Goat](/images/research/8496b8d1-4843-49ae-89d2-e857a28906ad/small/19296.jpg)
research Thymosin β4 Identified by Transcriptomic Analysis from HF Anagen to Telogen Promotes Proliferation of SHF-DPCs in Albas Cashmere Goat
Thymosin β4 helps increase hair growth in Cashmere goats.
research Induced pluripotent stem cell line MUSIi006-A derived from hair follicle keratinocytes as a non-invasive somatic cell source
Hair samples can be used to create stem cells easily and non-invasively.
![Stem cells, organoids and their applications for human diseases: Special issue of BMB Reports in 2023](/images/research/76e77705-b324-45bf-9209-3b48281b6f79/small/19136.jpg)
research Stem cells, organoids and their applications for human diseases: Special issue of BMB Reports in 2023
Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.
![Shushing down the epigenetic landscape towards stem cell differentiation](/images/research/4f61815b-e0ae-4420-b07b-91c7376f6239/small/19893.jpg)
research Shushing down the epigenetic landscape towards stem cell differentiation
The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.
![Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog](/images/research/e7b97f69-b9e9-4664-bd83-a4378b3d3064/small/19590.jpg)
research Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog
Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
![Hair follicle stem cell progeny heal blisters while pausing skin development](/images/research/6a0ad6bf-533d-477b-8b06-4e66d818e02e/small/30830.jpg)
research Hair follicle stem cell progeny heal blisters while pausing skin development
Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.
![Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis](/images/research/84cc8c1b-d56d-4a06-92c5-e2512740a3c1/small/22039.jpg)
research Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis
Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
![Next generation human skin constructs as advanced tools for drug development](/images/research/55d126ec-879f-4143-a3df-d26f8a9cf206/small/18204.jpg)
research Next generation human skin constructs as advanced tools for drug development
Advanced human skin models improve drug development and could replace animal testing.
![Lamins in development, tissue maintenance and stress](/images/research/c5e12d96-ef77-435d-ac93-ea8d35db2e3e/small/35495.jpg)
research Lamins in development, tissue maintenance and stress
Lamins are vital for cell survival, organ development, and preventing premature aging.
![The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development](/images/research/05508810-4c7d-426a-a981-67cb659c9197/small/34627.jpg)
research The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development
The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.