August 2023 in “Journal of Dermatological Treatment” This systematic review concluded that mesotherapy shows potential for improving hair growth outcomes, yet lacks standardized regimens and requires further large-scale trials to establish its efficacy and safe use.
This study found changes in the PGI2 pathway, especially in gene and protein expression, in diabetic mice, but did not observe PGI2-dependent vasomotor dysfunction.
November 2018 in “Journal of investigative dermatology, venereology and cosmetology” This study found that Biofield Energy Healing significantly increased the proliferation of human hair follicle dermal papilla cells in vitro, suggesting it may promote hair growth.
61 citations
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September 2024 in “Micromachines” This paper provides a comprehensive overview of the applications of electrospun nanofibers in non-invasive medical fields, highlighting their potential for health monitoring, personal protection, thermal regulation, and wound care, and discusses the challenges and future development paths for this technology.
48 citations
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July 2022 in “International Journal of Nanomedicine” This review discusses nanotechnology-based therapies for chronic wound healing and highlights their potential, but it reports no new clinical results.
36 citations
,
June 2015 in “International journal of toxicology” This study established a new mouse model for TCE-induced skin sensitization and reported that proinflammatory cytokines TNF-α, IFN-γ, and IL-2 significantly contribute to this sensitization process.
24 citations
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August 2021 in “Biologics” This review discusses the use of stem cells and stem cell-derived products in burn wound healing, highlighting various stem cell sources, associated signaling pathways, and delivery methods, but reports no new clinical results.
24 citations
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October 2022 in “Cell Regeneration” This study describes a new mouse model for vitiligo that mimics key clinical features such as skin depigmentation and CD8 + T cell infiltration, providing a useful tool for in-depth research and drug discovery.
21 citations
,
March 2022 in “Pharmaceuticals” This study found that Brigatinib-loaded nanospanlastics demonstrated enhanced cytotoxicity against lung cancer cells and improved drug stability and release compared to free Brigatinib.
15 citations
,
January 2023 in “Biomaterials Research” This review explores the application and implications of 3D bioprinting in plastic surgery but reports no new clinical results, emphasizing its potential benefits and challenges for future research.
13 citations
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November 2022 in “Chemical Science” This review discusses the use of inorganic-based biomaterials for hemostasis and wound healing, including various preparation methods and mechanisms, but reports no new clinical results.
13 citations
,
November 2021 in “Biomedicines” This review discusses the potential of plasma-activated liquid (PAL) in medical applications and highlights recent studies to inform researchers of its usage possibilities, but reports no new clinical findings.
7 citations
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August 2023 in “Dermatologic Surgery” In this study, researchers reported that a new skin-responsive FU excision device consistently succeeded in all patients of African descent, showing a mean graft transection rate of less than 10%, with skin thickness and firmness identified as major factors affecting graft attrition rate.
7 citations
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August 2020 in “Plastic and reconstructive surgery. Global open” In this study, QR 678 and QR 678 Neo formulations containing growth factors and peptides were found to be safe in vitro and promoted hair growth in vivo in an animal model, suggesting their potential as treatments for alopecia, including secondary alopecia post-chemotherapy.
6 citations
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August 2024 in “Frontiers in Bioengineering and Biotechnology” This study reviewed the use of 3D printing and bioprinting for tympanic membrane repair, comparing them with traditional materials and noting their clinical significance, while highlighting the need for further analysis of bio-ink selection strategies involving biopolymers, cells, and drugs.
5 citations
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May 2022 in “Biomedicines” This study found that the green alga Botryococcus terribilis and its novel compounds significantly promoted hair growth marker gene expression in hair follicle dermal papilla cells without cytotoxic effects.
5 citations
,
March 2017 in “Immunology and Cell Biology” This review discusses recent advances in biomedical imaging for cancer research, particularly highlighting improved imaging tools for studying solid tissue malignancies, and reports no new clinical results.
4 citations
,
July 2021 in “Journal of dermatology & dermatologic surgery” This review discusses the use of microneedling with a dermaroller for treating acne scars, hair loss, and wrinkles, and reports no new clinical results.
3 citations
,
April 2023 in “Quality Assurance and Safety of Crops & Foods” This study found that oil extracted from Prinsepia utilis seeds is physicochemically stable and suitable for use in manufacturing ketoconazole soap, which met quality control standards and may provide a cost-effective alternative to expensive additives in cosmetic and pharmaceutical applications.
3 citations
,
April 2022 in “Bioengineering” This review discusses pre-clinical research on ultrasound-mediated sonoporation for tissue regeneration and reports no clinical results; the authors suggest the method is safe and highlight challenges to clinical translation.
2 citations
,
July 2025 in “Biopolymers” This review explores the eggshell matrix as a potential sustainable and cost-effective alternative source for glycosaminoglycans, but highlights the need for further research to enhance extraction techniques and economic viability.
2 citations
,
November 2022 in “Biosensors” This study introduced a new spectrofluorometric method using a synthesized organic fluorophore to effectively analyze darolutamide and thalidomide in pharmaceutical preparations and biofluids.
1 citations
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July 2025 in “MedComm – Biomaterials and Applications” This review discusses the potential of microneedles in cancer diagnosis and treatment, highlighting advances and ongoing clinical trials, but reports no new results; it emphasizes the minimally invasive nature of this technology.
1 citations
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April 2023 in “International Journal of Molecular Sciences” This study found that Botryococcus terribilis ethanol extract significantly reduced inflammation markers in LPS-stimulated RAW264 cells, potentially via Axl inhibition and alteration of immune-related gene expression.
1 citations
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January 2023 in “Skin Appendage Disorders” This review suggests that radiofrequency devices may be effective for both hair removal and growth, depending on the RF modality, but further research is needed to clarify their efficacy and mechanisms.
July 2026 in “Advanced Science” In this study, researchers found that a scallop adhesive protein (Sbp9 Δ) forms strong adhesive coatings via disulfide-sticker strategies, which also promote hair regeneration in mouse models by activating Wnt signaling and enhancing angiogenesis, proving more effective than minoxidil for androgenetic alopecia.
February 2026 in “International Journal of Nanomedicine” This study demonstrated that engineered exosomes carrying EGF and FGF restored hair density and follicle integrity in an androgenetic alopecia mouse model by reactivating hair follicle growth factors, offering a novel therapeutic approach without immunogenic reactions or systemic toxicity.
December 2025 in “Pharmaceutics” This review highlights the potential of drug-loaded extracellular vesicles as a promising drug delivery platform but notes that clinical translation faces challenges due to variability in methods and the need for standardization and safety evaluation.
September 2025 in “Pharmaceutics” In this study, quercetin nanocrystals stabilized with glycyrrhizic acid were developed as a new treatment strategy for androgenetic alopecia, which significantly reduced DHT levels and improved hair regrowth in a mouse model, indicating synergistic potential for clinical application.
August 2025 in “Plastic and Aesthetic Research” This review discusses recent advancements in microneedle technology for hair loss treatment, highlighting their ability to enhance drug delivery and improve hair follicle survival in transplantation, while also exploring their potential integration with tissue engineering to address regeneration challenges.