Upcycling Eggshell Matrix for Sustainable Production of Glycosaminoglycans

July 2025 in “ Biopolymers ”

Emmanuel Cobbinah‐Sam, Idaresit Ekaette

glycosaminoglycans hyaluronic acid chondroitin sulfate

Studysummary This review explores the eggshell matrix as a potential sustainable and cost-effective alternative source for glycosaminoglycans, but highlights the need for further research to enhance extraction techniques and economic viability.

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The document reviews the potential of using eggshell matrix waste as a sustainable and abundant source for producing glycosaminoglycans (GAGs), which are crucial for pharmaceutical, nutraceutical, and biomedical applications. Eggshell-derived GAGs offer advantages such as uniform molecular weights, enhanced solubility, and reduced contamination risks compared to traditional animal and marine sources. The study highlights the high yield of GAGs from eggshell membranes and the environmental benefits of upcycling eggshell waste, which can reduce landfill emissions. However, challenges like high purification costs, regulatory hurdles, and the need for efficient extraction methods limit large-scale commercialization. Future research should focus on optimizing extraction techniques and addressing economic and regulatory barriers to enhance the feasibility of eggshell-derived GAG production.

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