2 citations
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January 2014 in “The Korea Journal of Herbology” This study found that Polygoni Multiflori Radix (PMR) reduced collagenase and elastase activity after UVB damage in fibroblasts, suggesting potential anti-aging properties for cosmetic use.
April 2023 in “Journal of Investigative Dermatology” In this study, a mouse model of scarring alopecia demonstrated significantly reduced CD200R expression in affected skin, which may contribute to immune attacks on hair follicles.
50 citations
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April 2018 in “Cosmetics” This study found that a topical gel formulation containing rice water demonstrated in vitro antioxidant activity and elastase inhibition, suggesting its potential as an anti-aging skincare ingredient.
December 2025 in “International Journal of Molecular Sciences” In this study, O. forskahlii seed oil was found to promote hair growth in rats and exhibit anti-aging effects on human skin cells by enhancing fibroblast proliferation and inhibiting inflammation and enzyme activity, indicating potential for cosmetic use.
September 2025 in “Journal of Applied Biological Chemistry” In a laboratory study, Grateloupia elata extract demonstrated antioxidant and anti-aging effects by scavenging free radicals, inhibiting collagenase and elastase, increasing procollagen production, and reducing MMP-1 secretion, suggesting its potential use in functional cosmetics.
February 2025 in “Intisari Sains Medis” This article explores the potential mechanisms by which polydeoxyribonucleotide (PDRN) could improve skin quality, slow aging, and enhance skin regeneration, but reports no new clinical findings.
This study found that the RADA-GHK and RADA-KGHK peptide hydrogels improved wound healing and cell growth without cytotoxicity, suggesting potential for use in skin regeneration.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reported that rice water, containing essential minerals and vitamins, shows promise in cosmetic and dermatological applications by acting as an anti-aging agent, hair growth promoter, and natural antidandruff treatment due to its antioxidant and antifungal properties.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports that rice water, rich in minerals, vitamins, and amino acids, shows potential in cosmetics and dermatology for its hydration, anti-aging, and antioxidant properties and effectiveness against dandruff, while also promoting hair growth and scalp health with natural cleansing abilities.
In this review, researchers highlighted the use of essential oils, praised for their antimicrobial and anti-inflammatory effects, in treating a variety of conditions, and noted their emerging role in dermocosmetics for issues like hyperpigmentation, acne, and skin aging.
January 2016 in “SpringerBriefs in bioengineering” This article discusses the structure and function of the skin's epidermis, detailing its role as a protective barrier and nutrient exchange system, without presenting new research findings.
55 citations
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August 2015 in “AAPS PharmSciTech” This study reports that a newly developed polyherbal phospholipid complex cream containing Citrus auranticum and Glycyrrhiza glabra extracts improved polyphenol retention in the skin, suggesting potential as an anti-aging cosmeceutical.
10 citations
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November 2023 in “Frontiers in Pharmacology” In this study, researchers developed a self-assembling hydrogel called RADA-PDGF2 and found it to accelerate wound closure in a mouse model due to its pro-proliferative and pro-migratory properties, without causing cytotoxicity or immunogenicity.
October 2009 in “The American Journal of Gastroenterology” This case report suggests that isolated amylase deficiency can lead to failure to thrive in children, and pancreatic enzyme supplementation may improve associated symptoms.
This study explored new molecular structures as potential COVID-19 treatments, identifying a compound called Hit15 that inhibited viral infection in lab settings and reduced inflammation markers in human neutrophils, suggesting further development is warranted.
62 citations
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September 2014 in “PLoS ONE” This study identified distinct human and bacterial protein profiles in sebaceous follicular casts, with acne samples showing proteins linked to inflammation and normal samples showing proteins involved in stress protection.
61 citations
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January 2018 in “Cosmetics” This review highlights the potential of coffee silverskin's bioactive compounds in combating skin aging and related conditions, suggesting it as a promising natural ingredient for cosmetics due to its antioxidant, anti-inflammatory, and anti-aging properties.
50 citations
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November 2010 in “Otolaryngologic Clinics of North America” This review discusses the oral manifestations associated with hematologic conditions and nutritional deficiencies, without presenting new research results; it emphasizes the impact of blood disorders and vitamin deficiencies on oral health.
19 citations
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November 1993 in “Mammalian Genome” This study reports that transgene insertion in homozygous transgenic mice causes irreversible hair loss and impaired immune function, linked to interruption of the hairless locus on Chromosome 14.
15 citations
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January 1995 in “Archives of Dermatological Research” This study suggests that minoxidil is a potent stimulator of elastin expression in embryonic skin fibroblasts, primarily affecting elastin mRNA levels, without impacting cell proliferation during the stationary phase.
14 citations
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January 2006 in “Skin pharmacology and physiology” This study found that procyanidin oligomers from apples and barley may stimulate hair growth by promoting hair epithelial cell proliferation and protecting them from apoptosis via MEK activation in a murine model.
2 citations
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October 2021 in “Egyptian Journal of Chemistry” In this study, researchers used pumpkin aqueous extract to create iron nanoparticles, finding them effective at inhibiting harmful bacteria found in burn and wound infections, as well as promoting burn healing and hair growth in a laboratory mouse model.
2 citations
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April 2016 in “Medical Hypotheses” This discussion of antioxidant use in pressure ulcer prevention highlights failed clinical trials but does not rule out ROS involvement or the potential efficacy of other antioxidants.
April 2023 in “IP Indian journal of clinical and experimental dermatology” This article reviews the pathogenesis, complications, and management of lichen planus, especially its persistent oral form, and highlights the need for further prospective studies.
June 2020 in “International journal of medical science and clinical invention” This review discusses the uses of Achillea millefoilum described by Ibn Rushd, finding scientific support for its applications in treating alopecia and skin disorders.
9 citations
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September 2009 in “Journal of Cutaneous Medicine and Surgery” This study reports cases of androgenetic alopecia patients with depigmented macules on sun-exposed scalp areas, suggesting potential ultraviolet-induced scalp leukoderma not covered in existing dermatology texts.
2 citations
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August 2023 in “Die Dermatologie” This review discusses the molecular pathology of progeroid syndromes and reports no new results; the authors emphasize understanding these mechanisms to develop treatments and potentially improve quality of life for affected individuals.
April 2015 in “Reactions Weekly” Some elderly men had healing problems after using imiquimod and diclofenac for skin conditions on their scalps.
1160 citations
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November 2018 in “Physiological Reviews” This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.
556 citations
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September 2008 in “Genes & Development” This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.