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Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Inactive hair follicle stem cells help prevent skin cancer.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

Hair usually grows back 1-3 months after treatment for anagen effluvium, and children with Loose Anagen Hair Syndrome often improve by adolescence.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Mice with human skin protein K8 had more skin problems and cancer.

The conclusion is to use scalp cooling, gentle hair care, and treatments like minoxidil for managing hair loss from chemotherapy, and stresses the need for more research and collaboration in this area.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

A gene variation is linked to hair thickness in Asians.

A blood pressure drug, diltiazem, may also help treat influenza.

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.