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    Did you mean EGFR inhibitors?
    Glossary EGFR inhibitors

    block cell growth signals to treat certain cancers

    EGFR inhibitors, also known as Epidermal Growth Factor Receptor inhibitors, are a class of drugs that block the activity of the EGFR, a protein on the surface of cells that helps them grow and divide. By inhibiting this receptor, these drugs can slow down or stop the growth of certain types of cancer cells that rely on EGFR for proliferation. They are commonly used in the treatment of cancers such as non-small cell lung cancer and colorectal cancer.

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    Research 30 of 1000+

    1. Effets secondaires cutanéo-muqueux des nouvelles molécules anticancéreuses: Inhibiteurs de l'EGF-R, inhibiteurs de tyrosine kinase et stabilisateurs du fuseau mitotique 2011
    2. Classification and management of skin, hair, nail and mucosal side-effects of epidermal growth factor receptor (EGFR) inhibitors European journal of cancer · 2007 · 138 citations
    3. Persistent hair growth during treatment with the EGFR inhibitor erlotinib Dermatology Online Journal · 2009 · 39 citations
    4. Semiology of skin toxicity associated with epidermal growth factor receptor (EGFR) inhibitors Supportive Care in Cancer · 2012 · 38 citations
    5. Cutaneous side-effects of EGFR inhibitors and their management. PubMed · 2011 · 38 citations
    6. Erosive Pustular Dermatosis of the Scalp-Like Eruption due to Gefitinib: Case Report and Review of the Literature of Alopecia Associated with EGFR Inhibitors Dermatology · 2012 · 36 citations
    7. The management of EGFR inhibitor adverse events: a case series and treatment paradigm International Journal of Dermatology · 2012 · 32 citations
    8. EGFR Inhibitors and Cutaneous Complications: A Practical Approach to Management Oncology and therapy · 2017 · 29 citations
    9. Rash from EGFR inhibitors: Opportunities and challenges for palliation Current Oncology Reports · 2008 · 18 citations
    10. Network pharmacology-based preventive effect of XZF on cutaneous toxicities induced by EGFR inhibitor Biomedicine & Pharmacotherapy · 2020 · 10 citations
    11. EGFR inhibitor-induced folliculitis decalvans: a case series and management guidelines Anti-Cancer Drugs · 2023 · 7 citations
    12. Treatment of Cultured Sebocytes with an EGFR Inhibitor Does Not Lead to Significant Upregulation of Inflammatory Biomarkers Annals of Dermatology · 2011 · 3 citations
    13. PRIDE Complex (Papulopustules and/or Paronychia, Regulatory Abnormalities of Hair Growth, Itching, Dryness Due to EGFR Inhibitors) JEADV Clinical Practice · 2025
    14. Erosive pustular dermatosis of the scalp due to EGFR inhibitors: A multicentric study by EADV task force of ‘Dermatology for Cancer Patients’ Journal of the European Academy of Dermatology and Venereology · 2025
    15. 566 Staphylococcus epidermidis for the topical treatment of epidermal growth factor receptor (EGFR) inhibitor-induced dermal toxicity Journal of Investigative Dermatology · 2024
    16. Folliculitis Decalvans-like Alopecia During Treatment With EGFR Inhibitors for Lung Cancer: A Case Series of 6 Patients Dermatology practical & conceptual · 2023
    17. Síndrome PRIDE: una práctica forma de identificar los efectos adversos cutáneos de los inhibidores del EGFR Revista Medicina Cutánea Ibero-Latino-Americana · 2021
    18. 422 Human hair follicles express PD-L1, whose expression is down-regulated by EGFR and MEK inhibitors ex vivo. A potential mechanism for EGFR inhibitor induced sterile folliculitis Journal of Investigative Dermatology · 2019
    19. MARIO LACOUTURE: How Do I Treat a Patient with Dermatologic Toxicities to EGFR Inhibitors? Oncology times · 2011
    20. 861 EGFR/MEK inhibitor therapy induces partial hair follicle immune privilege collapse in vivo and ex vivo Journal of Investigative Dermatology · 2022
    21. Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege bioRxiv (Cold Spring Harbor Laboratory) · 2023
    22. Anti-EGFR mechanism of action: antitumor effect and underlying cause of adverse events. PubMed · 2006 · 91 citations
    23. Unexpected hair growth induced by gefitinib treatment in two patients with EGFR gene mutation-positive adenocarcinoma of the lung 2015 · 1 citations
    24. EGFR signaling is required for regenerative proliferation in the cochlea: Conservation in birds and mammals Developmental Biology · 2012 · 53 citations
    25. IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes 2019 · 32 citations
    26. Skin toxicity caused by EGFR antagonists—An autoinflammatory condition triggered by deregulated IL‐1 signaling? Journal of Cellular Physiology · 2008 · 19 citations
    27. JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia EMBO Molecular Medicine · 2024 · 8 citations
    28. Papulopustular eruptions associated with EGFR-pathway-related targeted therapies: clinical spectrum, evidence boundaries, folliculocentric inflammation, and management considerations Frontiers in Oncology · 2026
    29. Cutaneous Adverse Effects of EGFR Therapy in Breast Cancer Treatment Clinical and Translational Science · 2025
    30. 59 Scarring alopecia is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege 2023