New cancer drugs can cause skin side effects like rashes, dry skin, hair changes, and nail problems.
9 citations,
March 2018 in “International journal of molecular sciences” Allopregnanolone changes gene expression in glioblastoma cells.
62 citations,
July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
70 citations,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
11 citations,
January 2000 in “Journal of Cutaneous Pathology” Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
82 citations,
May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
11 citations,
August 1997 in “Expert Opinion on Therapeutic Patents” Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
13 citations,
March 2017 in “Genomics” Genomic approach finds new possible treatments for hair loss.
2 citations,
October 2015 in “Human Gene Therapy” The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
59 citations,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
82 citations,
March 2013 in “PLoS ONE” Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.
277 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
February 2024 in “Journal of Health Science and Medical Therapy” ADAM17 could be a potential target for treating PCOS.
21 citations,
December 2016 in “PLOS ONE” Scientists made skin stem cells from other human cells with over 97% efficiency, which could help treat skin conditions.
December 2023 in “Communications biology” Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.
March 2023 in “Anais Brasileiros De Dermatologia” Topical minoxidil is the best-supported treatment for female hair loss, but personalized plans are needed.
31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.
6 citations,
December 2019 in “Frontiers in genetics” GLI1 might protect against the start of skin cancer and is not linked to cancer severity.
8 citations,
September 2013 in “Molecular carcinogenesis” Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
1 citations,
December 2023 in “Curēus” Tadalafil is effective for treating urinary symptoms in men with BPH.
11 citations,
October 2017 in “Journal of Investigative Dermatology” Applying certain inhibitors to the skin can promote hair growth without harming cells.
4 citations,
January 2020 in “International Journal of Trichology” Too much epidermal growth factor can cause hair loss.
26 citations,
June 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Regenerative therapies show promise for treating vitiligo and alopecia areata.
77 citations,
March 2001 in “Clinics in Dermatology” Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
12 citations,
December 2010 in “Journal of thoracic oncology” New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.
2 citations,
January 2019 in “Annals of Dermatology” Certain gene variations in EGF and EGFR may increase the risk of alopecia areata in Koreans.
4 citations,
March 2012 in “Annals of oncology” New treatment with green tea polyphenols and nicotinamide improves skin problems from cancer therapy.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.