Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This research found that deleting the SLC3A2 gene in hair follicle stem cells disrupts their maintenance and proper differentiation, leading to hair follicle growth defects and altered skin regeneration through a YAP/Taz-dependent pathway.

This review examines how biochemical and biophysical induction factors influence cell fate in tissue engineering and reports no new experimental results.

This review discusses regenerative medicine and explores the potential of molecular imaging in enhancing personalized therapies, but it reports no new research results.

This review synthesizes recent research on how Wnt signaling regulates skin, hair follicle, and nail regeneration, highlighting its compartment-specific roles and discussing targeted strategies for treating conditions like alopecia, chronic wounds, and skin cancer.

This review examines recent advances in androgenetic alopecia treatment, highlighting how multifunctional plant extracts combined with nanotechnology could improve topical therapy efficacy by enhancing local drug bioavailability and targeting, addressing limitations of existing treatments.

In this study, maternal melatonin implantation in pregnant rabbits reduced hair follicle cell apoptosis and increased hair follicle density in their neonatal offspring, suggesting a beneficial impact on hair follicle development mediated through specific molecular pathways.

This chapter reviews the clinical evidence of adding platelet-rich plasma to lipofilling for tissue regeneration, with suggestions of benefits in skin rejuvenation and wound healing, but lacks well-designed trials.

This study identified genetic variants in the DSG4 gene associated with the autosomal recessive form of monilethrix in Chinese patients, expanding the understanding of its phenotypic spectrum and clinical features.

This research observed that nanoliposomes delivering a combination of bioactive peptides significantly promoted hair growth in vitro and in vivo by enhancing the proliferation and function of hair growth-targeted cells in C57BL/6 mice, suggesting a promising approach for treating androgenetic alopecia.

In this case report, a 72-year-old female with Cronkhite-Canada syndrome showed significant improvement in symptoms and gastrointestinal polyps after hormone therapy and additional treatment.

In this study, iPSC-derived epidermal organoids demonstrated potential as a novel tool for regenerative medicine by producing high-performance extracellular vesicles that promote proliferation, migration, and angiogenesis in cell-free therapies for wound healing.

Fusarium sp. strain K-23 helps Arabidopsis plants grow better in salty soil by promoting root hair growth.

This study demonstrates that Wnt signaling plays a crucial mechanoregulatory role in skin regeneration by influencing cellular responses to substrate rigidity, which promotes hair follicle regeneration in the wound-induced hair neogenesis model.

This case study found that a 9-year-old girl with trichorhinophalangeal syndrome type 1 experienced significant improvements in hair density and length after 4 months of topical minoxidil treatment, suggesting its therapeutic potential for this condition.

This study reports the discovery of mutations in the PADI3, TGM3, and TCHH genes as molecular genetic causes of uncombable hair syndrome in children, indicating an autosomal-recessive inheritance pattern.

This publication provides a standardized nomenclature for classifying microscopic lesions in laboratory rat and mouse skin, aiming to harmonize international toxicological research.

This study found that overexpression of the calcium sensing receptor in transgenic mice accelerates epidermal differentiation and hair growth, suggesting its role in enhancing calcium signaling and interaction with other pathways.

This study found that extracellular vesicles derived from hair follicle mesenchymal stromal cells demonstrated similar potential to those from adipose tissue in promoting cell proliferation and migration, enhancing angiogenesis, and protecting cells under stress, suggesting promise for chronic wound treatment.

Combining FUE hair transplantation with PRP improves hair density and patient satisfaction in scarring alopecia.

Genetic studies on hair traits can improve understanding of health and disease.

This study found that plucked hair follicles can serve as a practical and scalable source for regenerative medicine, as researchers successfully isolated and expanded keratinocytes and mesenchymal stem cells for potential cell-based and cell-free therapies, demonstrating significant wound-healing bioactivity in vitro.

This study found that bovine milk-derived exosomes (MEV-miRNAs) significantly increased hair follicle dermal papilla cell viability and up-regulated key WNT signaling components in human hair follicles, suggesting potential therapeutic benefits for androgenetic alopecia and telogen effluvium through modulation of hair growth pathways.

This case report describes a rare genetic mutation causing congenital hypotrichosis, where a 2-year-old girl showed some improvement in hair growth with topical minoxidil treatment, supporting its potential use for this condition.

In this review, it is discussed how mesenchymal stem cell aggregation plays a crucial role in organ development and has potential applications in organ regeneration through tissue engineering.

This review article highlights recent progress and challenges in stem cell transplantation for regenerative medicine, emphasizing its potential in tissue repair for conditions like bone and cartilage injuries, neurological disorders, and blood diseases, while stressing the importance of overcoming current obstacles for future advancements.

This study found that human adipose-derived stem cells co-cultured on a collagen sponge scaffold showed increased differentiation into keratinocytes, suggesting potential for improved skin wound healing.

This review examines the regeneration capabilities of skin, oesophagus, and oral mucosa, highlighting the oral mucosa's unique scarless healing properties and the potential of cell therapy to improve scar reduction in wound healing.

This review discusses the potential of stem cell-derived extracellular vesicles for improving diabetic wound healing and highlights their mechanisms, limitations, and challenges, but provides no new clinical findings.

This study found that combining ultrapulsed fractional CO2 laser with bovine basic fibroblast growth factor significantly improved acne scars more effectively and safely compared to laser therapy alone.

In this study, researchers found that treating dermal papilla cells with synovial fluid and laser photobiomodulation increases the expression of chondrocyte marker genes, indicating potential promotion of chondrogenic differentiation.