Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review highlights the regenerative abilities of *Xenopus laevis*, focusing on how tadpoles regrow complex tail structures and the cellular and molecular mechanisms behind this. It underscores *X. laevis* as a valuable model for understanding regeneration, with insights potentially advancing regenerative medicine.

This study found that patients with severe alopecia areata demonstrated reduced corneal sensitivity and increased corneal staining, and exhibited altered topographic and biomechanical eye parameters compared to controls, suggesting a possible increased risk of keratoconus and the necessity for regular ophthalmological exams.

In this study, researchers found that miR-199a-3p plays a regulatory role in hair follicle development via the PTPRF/β-catenin axis and established a mouse model of alopecia areata by downregulating this small RNA, suggesting its potential value in studying alopecia diseases.

In this narrative review, the authors discuss regenerative substances like platelet-rich fibrin and mesenchymal stem cells in biological aesthetics, noting that while these methods show promise for regeneration, their safety, effectiveness, and durability remain uncertain due to limited and heterogeneous evidence.

This review article explores the potential systemic nature of alopecia areata, highlighting the association with ocular abnormalities and suggesting that shared pathogenic pathways may lead to eye symptoms occurring at younger ages than usual.

This review highlights that skin organoids, advanced three-dimensional models mimicking human skin, are emerging as effective alternatives to traditional culture models and human skin, overcoming limitations of two-dimensional systems and ethical concerns, and are being increasingly used in areas like developmental biology and disease modeling.

This review compiles existing information on the pathogenesis of androgenetic alopecia, highlighting its genetic, hormonal, and environmental factors, but reports no new clinical findings.

This review explores the role of lymphatic vessels in skin regeneration and hair follicle growth, emphasizing their interactions with hair follicle stem cells and potential implications for regenerative therapies, but reports no new clinical results.

This study found that differentiated cells of the corneal epithelium can be converted to hair and interfollicular epidermis through a multistep process involving dermal developmental signals.

This study observed that overexpression of TGF-alpha in transgenic mice led to thicker epidermis and stunted hair growth, particularly in regions with normally thick skin and low hair density.

This review article highlights recent progress and challenges in stem cell transplantation for regenerative medicine, emphasizing its potential in tissue repair for conditions like bone and cartilage injuries, neurological disorders, and blood diseases, while stressing the importance of overcoming current obstacles for future advancements.

This review covers advancements in skin repair and rejuvenation technologies, highlighting potential benefits of stem cell therapy, bioengineered skin substitutes, PRP, exosome therapies, and gene editing for conditions such as chronic wounds and genetic disorders, though challenges in accessibility, safety, and long-term effectiveness remain.

This study found that impaired TCF/Lef1 signaling in mice leads to significant skin barrier defects due to altered lipid metabolism and epidermal differentiation.

This review covers the structure, development, cycle, and molecular regulation of hair follicles but does not report new results, aiming to offer insights for addressing hair follicle-related diseases.

Red and infrared light therapy improves hair growth in balding patients.

In this study, detailed examinations of alopecic lesions in two female Cronkhite-Canada syndrome patients suggested hair regrowth might occur without systemic corticosteroids if not required for gastrointestinal treatment, and hair loss may begin with anagen-telogen transition.

Lactic acid cream can help improve skin bumps known as eruptive vellus hair cysts.

In this case report, a patient with Cronkhite-Canada Syndrome developed colon cancer and liver metastasis despite hormone therapy, highlighting the need for regular monitoring and early detection strategies.

This article describes a protocol for using bioengineered techniques to regenerate functional hair follicles and their stem cell niches by manipulating epithelial and mesenchymal cells.

Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.

This article discusses the development of the regenerative medicine field based on stem cells' capacity for in vitro differentiation, rather than actual organ or tissue regeneration.

This review discusses recent findings on hair follicle morphogenesis and regeneration, focusing on molecular signals and stem cells, and suggests that understanding these processes may aid in developing new strategies for wound healing.

This review discusses potential cell sources and bioengineering strategies for regenerating hair follicles with functional cycling, reporting no new results.

This study found that the DNA methylation status of skin samples from cashmere goats was higher during the telogen stage compared to the anagen stage, identifying genes potentially important for hair follicle development and growth.

This review discusses diagnostic strategies for pediatric hair loss, emphasizing the importance of thorough examinations and dermoscopy for accurate diagnosis, and reports no new research findings.

Hair follicle stem cells and mitochondria are key for hair growth, and targeting their activity could lead to new hair loss treatments.

This chapter reviews the clinical features, diagnosis, treatment, and prognosis of various non-hormonal, non-infectious alopecias without providing new clinical findings.

This paper reviews the role of ATP-dependent chromatin remodeling complexes in epidermal homeostasis, hair regeneration, and skin repair, noting contributions to 3D-genomic organization and suppression of UV-induced hyper-proliferation, without presenting new results.

This study observed that estrogen receptor content was lower in white hair compared to black hair, with the lowest levels recorded in male white hair among participants aged 50-56.

This article discusses congenital atrichia and presents no new clinical findings.