December 2021 in “Journal of clinical images and medical case reports” This review compares mesotherapy and PRP for hair loss but reports no new clinical results; the authors highlight the need to understand their differences for optimal treatment choices.
34 citations
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December 2012 in “Indian Journal of Dermatology, Venereology and Leprology” Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.
September 2021 in “Farmacja Polska” In this summary of needle mesotherapy's role in treating alopecia, the researchers highlight its use in delivering beneficial substances directly to the skin or hair follicles, showing hair loss reduction after one treatment and hair regrowth after several sessions, although contraindications exist for certain populations.
August 2025 in “SciELO (SciELO Preprints)” In this review, the authors assessed the efficacy of mesotherapy for alopecia treatment, finding that combining mesotherapy with minoxidil, PRP, or growth factors significantly improves hair density and thickness but noted the need for standardized protocols and larger studies to confirm long-term effectiveness.
January 2022 in “Journal of Cutaneous and Aesthetic Surgery” Using truncal anesthesia on the supraorbital nerve reduces pain in hair loss treatments and improves patient comfort.
This review found that mesotherapy could improve hair density and reduce hair fall in androgenetic alopecia, especially when combined with other treatments, but lacks standardized protocols and long-term safety data.
September 2023 in “Forum Dermatologicum” This source discusses androgenetic alopecia, noting that male patients may transition from topical minoxidil to its systemic form or from finasteride to dutasteride for potentially better results, while female patients might require extensive lab testing to identify hyperandrogenism due to environmental triggers.
This comprehensive review analyzes androgenetic alopecia treatments, discussing the mechanisms, costs, efficacy, and safety of FDA-approved drugs like minoxidil and finasteride, as well as newer non-FDA-approved options that have shown effectiveness across various studies.
May 2026 in “Skin Appendage Disorders” This study found that combining platelet-rich plasma with systemic therapies for androgenetic alopecia may result in greater improvements in hair density and width than using PRP alone, though the differences were not statistically significant.
23 citations
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October 2018 in “Expert Opinion on Drug Safety” This review discusses the safety concerns associated with new treatments for non-scarring alopecias, highlighting that while these therapies such as JAK inhibitors and oral minoxidil show efficacy in hair regrowth, their safety profiles vary significantly, requiring careful consideration of benefits and risks.
1 citations
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July 2022 in “JEADV Clinical Practice” This abstract outlines a guide reviewing both FDA-approved and off-label therapies for androgenetic alopecia and proposes treatment algorithms based on scientific research, highlighting a gap in common treatments for this prevalent condition.
February 2024 in “Actas Dermo-Sifiliográficas” This study involved a Delphi-method consensus from 34 Spanish dermatologists, outlining structured recommendations for managing androgenetic alopecia based on available scientific evidence and expert opinions, aiming to guide clinical practice amid limited treatment approvals and varying effectiveness.
14 citations
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August 2013 in “Facial Plastic Surgery Clinics of North America” This review discusses current and emerging medical therapies for androgenetic alopecia but reports no new clinical findings, emphasizing the importance of stabilizing the condition as a complement to surgical hair restoration.
December 2025 in “Medicine - Programa de Formación Médica Continuada Acreditado” This review synthesizes recent advancements in clinical trichology, highlighting updates on androgenetic alopecia treatments like low-dose oral minoxidil, 5α-reductase inhibitors, and other therapeutic options for various alopecia types, including telogen/anagen effluvium and alopecia areata, and detailed approaches for scarring alopecias and pediatric trichology.
October 2023 in “University of Zadar Institutional Repository” This paper describes androgenic alopecia as a hereditary form of hair loss influenced by androgens, outlining its diagnosis, treatment options like minoxidil and finasteride, and the importance of psychological support due to its impact on quality of life.
April 2022 in “Medicina estética” This review of female androgenetic alopecia treatments reports limited therapeutic options due to unclear pathogenesis, with minoxidil as the only FDA-approved treatment and adjuvant therapies under investigation.
October 2021 in “Cosmoderma” This review summarizes existing knowledge on diffuse and patterned alopecia, emphasizing recent advancements in treatment beyond FDA-approved options, but it reports no new clinical findings.
July 2018 in “Elsevier eBooks” This review discusses novel treatments for androgenetic alopecia, including therapies like platelet-rich plasma and adipose-derived stem cells, and reports no new clinical results.
April 2021 in “Journal of Cosmetic Dermatology” Stem cell treatment improved hair density in female hair loss patient.
March 2026 in “Preprints.org” This study reviewed evidence for six minimally invasive treatments for androgenetic alopecia, finding consistent support for platelet-rich plasma and topical finasteride, while other options like microneedling and intradermal dutasteride showed promise but need further and standardized research.
This study found that androgenetic alopecia patients treated with a combination of PRP and systemic therapy experienced greater but non-significant improvements in hair density and width compared to PRP monotherapy, without additional adverse effects, suggesting potential benefits for further exploration of combination regimens.
In this study, PRP combined with systemic therapy for androgenetic alopecia showed higher, but not statistically significant, improvements in hair density and width compared to PRP alone, with no increase in side effects; further prospective studies are recommended.
January 2024 in “Journal of Cosmetic Dermatology” Microneedling combined with other treatments significantly improves hair growth in people with hair loss and is safe.
December 2025 in “International Journal of Innovative Technologies in Social Science” This review identified emerging therapies for androgenetic alopecia, such as low-dose oral minoxidil and stem cell-based treatments, which show promise for improved hair loss management but require standardized protocols and large-scale trials for further validation.
May 2024 in “Journal of cosmetic dermatology” The study concluded that dutasteride 0.5 mg daily for 24 weeks was the most effective monotherapy for increasing hair density in men with androgenetic alopecia, compared to other interventions.
February 2026 in “Journal of Drugs in Dermatology” In this series, patients experienced alopecia with limited regrowth following mesotherapy, indicating possible lasting aesthetic consequences and suggesting the need for careful technique and close follow-up, as the condition might be underrecognized.
October 2024 in “JAAD Case Reports” In this retrospective analysis, dutasteride mesotherapy was used in 10 patients with androgenetic alopecia and resulted in hair density and width changes measured at the scalp, but specific efficacy results are not detailed in the abstract.
2 citations
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March 2014 in “Turkderm” Mesotherapy and platelet-rich plasma treatments may help with hair loss, but their safety and effectiveness are still uncertain.
In this study, researchers found that adding zygomaticotemporal nerve blocks to supratrochlear and supraorbital nerve blocks in mesotherapy lowered pain significantly during and after the procedure for hair regrowth in alopecia patients.
November 2019 in “Journal of Aesthetic Nursing” This article reviews the classifications and characteristics of androgenic alopecia and provides no new clinical results; it emphasizes the importance for aestheticians to understand current treatment evidence.