Persistent Alopecic Patches Following Dutasteride Mesotherapy for Female Androgenetic Alopecia: A Case Series

    February 2026 in “ Journal of Drugs in Dermatology ”
    Carlos M. Nogueira, Filipa Osório
    From the encyclopedia
    Dutasteride →

    Heavy duty finasteride that comes with higher risks

    Mesotherapy →

    technique to inject very small amounts of beneficial chemicals into the scalp

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    Studysummary In this series, patients experienced alopecia with limited regrowth following mesotherapy, indicating possible lasting aesthetic consequences and suggesting the need for careful technique and close follow-up, as the condition might be underrecognized.
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    This case series reports on 3 female patients with androgenetic alopecia (AGA) who developed persistent alopecic patches following mesotherapy with dutasteride. Despite the increasing popularity of localized scalp injections to mitigate systemic side effects of 5-alpha-reductase inhibitors, complications can occur. The first case involved a 44-year-old woman who, after a single session of dutasteride mesotherapy, experienced persistent hair loss. The treatment involved a 0.025% concentration of dutasteride mixed with an anesthetic solution, administered with 4 mm, 30G needles. This highlights the potential risks associated with mesotherapy for AGA, despite its intended benefits.
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