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Brepocitinib 30mg is most effective for moderate-to-severe alopecia areata, but ritlecitinib 50mg may offer a better balance of safety and effectiveness.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

New tests detect finasteride and dutasteride in urine quickly and easily.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

5ARI treatment improves hair growth in older men with minimal side effects.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.