139 citations,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
136 citations,
May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
47 citations,
February 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
43 citations,
February 2020 in “Clinica chimica acta” Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
35 citations,
August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
25 citations,
June 2021 in “Developmental Cell” Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.
25 citations,
July 2019 in “Experimental Dermatology” Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
21 citations,
January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
21 citations,
February 2016 in “Reproductive Biomedicine Online” The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.
9 citations,
March 2018 in “International Journal of Cancer” Men with frontal male pattern baldness may have a higher risk of gastric cancer.
January 2024 in “Burns and trauma” The skin microbiome helps heal wounds and can be targeted to improve healing.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
November 2022 in “CARDIOMETRY” A group has developed therapies that show promise for treating cancer and various other conditions.
April 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain small molecules can help regrow hair by turning on the body's cell cleanup process.
10 citations,
November 2021 in “Biomedicines” Some therapies using stem cells and platelet-rich plasma may help treat osteoarthritis, but more research is needed to ensure they are safe and effective.
1 citations,
April 2022 in “Regenerative Therapy” Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
133 citations,
July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
72 citations,
November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
31 citations,
November 2020 in “International journal of molecular sciences” Adipokines affect skin health and could be targeted for treating skin diseases.
14 citations,
June 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
12 citations,
August 2022 in “Biochemical Journal” Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
7 citations,
August 2020 in “Genes” Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
1 citations,
March 2024 in “International journal of molecular sciences” Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
88 citations,
June 2019 in “Cell reports” Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.
38 citations,
February 2021 in “Journal of Investigative Dermatology” Aging slows wound healing due to weaker cells and immune response.
30 citations,
February 2022 in “Pharmaceutics” 3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
9 citations,
December 2022 in “Phytomedicine” More high-quality research is needed to recommend flavonoids and saponins for clinical use.
8 citations,
May 2023 in “Gels” Chitosan hydrogels are promising for repairing blood vessels but need improvements in strength and compatibility.
2 citations,
June 2023 in “Gels” Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.