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This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.

This study reported that larger caffeine nanocrystals, at 694 nm, increased caffeine bioavailability via transfollicular penetration compared to smaller nanocrystals, especially in long-term serum concentration measurements.

This study explores how applying fundamental physics in microgravity environments could potentially double the bioavailability of space pharmaceuticals by excluding substrate concentrations during preparation, though results require validation through future experiments or clinical trials.

This position paper from the Italian Mesotherapy Society discusses the application of intradermal therapy based on scientific evidence, highlighting its potential benefits for certain localized conditions, although it acknowledges the lack of randomized clinical trials for some uses.

This study found that coated microneedles promoted drug release effectively, comparable to marketed minoxidil solutions, with stable performance over 30 days at high temperatures.

This study reported that pentoxifylline-loaded liposomes, optimized using a statistical design method, achieved a maximum encapsulation efficiency of 84.23% and a controlled 72-hour drug release, potentially improving therapeutic delivery of the drug with limited bioavailability.

This article discusses the challenges in evaluating drug effects on hair growth and emphasizes DNA-flowcytometry as a reliable method for this purpose, without reporting new clinical results.

This review describes advanced drug delivery systems for dithranol aimed at overcoming stability issues and skin irritation seen in conventional formulations, highlighting options like nanoparticles and liposomes for improved psoriasis treatment.

In this study, the researchers developed and optimized a bilayer tablet containing Tamsulosin and Finasteride, achieving sustained and immediate drug release with favorable release kinetics, including first-order and anomalous diffusion mechanisms, through in vitro testing.

In this study, the release rate of Finasteride from Eudragit matrix tablets was found to be significantly influenced by the drug/Eudragit ratio and polymer viscosity, with formulation F9 being the most effective.

This study reviews the potential of electrospun nanofiber mats as innovative drug delivery systems for wound healing, emphasizing their ability to enhance drug release, improve cell adhesion, and promote tissue regeneration by incorporating antibiotics, growth hormones, or stem cells.

This study found that FucoPol hydrogel membranes can effectively deliver model drugs such as caffeine and diclofenac sodium via different loading methods, with notable mechanical and release properties, suggesting their potential as platforms for topical drug delivery.

In this study, candidate compound 39 demonstrated potent androgen receptor antagonism and faster hair-growth efficacy in a mouse model compared to pyrilutamide, while maintaining favorable safety and pharmacokinetic profiles, suggesting potential for topical use in androgenic alopecia.

This study found that cyclosporine A can alter lipid bilayer properties and does so at a slower rate, suggesting conformational shifts may facilitate its membrane crossing.

This study found that nanostructured lipid carriers could serve as a promising vehicle for topical Acitretin delivery in psoriasis treatment, potentially reducing oral side effects and enhancing patient compliance.

This review discusses the signaling mechanisms of RAAS, the current drugs targeting RAAS, their limitations, and suggests innovative strategies for developing new therapeutics but reports no new results.

In this study, cinnamic acid in solution form showed strong antifungal activity against Microsporum canis, but when incorporated into hydrogels, the acid's diffusion and resulting antifungal performance decreased, though it maintained effectiveness for potential prolonged exposure.

This review summarizes recent advancements in follicular targeting for drug delivery via hair follicles and calls for pilot studies in humans to explore potential clinical applications.

This study found that finasteride ethosome formulations with specific ethanol and soya lecithin concentrations significantly enhanced transdermal drug delivery compared to a potential nanogel.

This report discusses the various causes and clinical assessment of madarosis, emphasizing the importance of recognizing and diagnosing associated vision or life-threatening conditions, without presenting new findings.

In vitro, this study found that PTX and HU SF-FA NLCs showed greater cytotoxicity and apoptosis in ovarian cancer cells than pure paclitaxel, suggesting promise as a targeted drug delivery platform.

This study evaluated niosome-based gels for delivering salicylic acid topically to treat acne vulgaris and found that the formulation SANG5, using Carbopol 940 and nutmeg oil, demonstrated the best drug release profile.

This review highlights how cyclodextrin-polysaccharide hybrids can advance drug delivery and environmental cleanup by improving the solubility and stability of hydrophobic molecules, serving as promising platforms for biomedical applications and efficient sorbents for wastewater treatment.

In this study, researchers found that finasteride undergoes second-order alkaline degradation kinetics and that its degraded form negatively impacts cell proliferation, highlighting the need for careful handling in pharmaceutical manufacturing and storage.

This review highlights the rapid advancements in 3D bioprinting techniques, emphasizing their role in enhancing regenerative therapy, drug delivery, and bioengineering applications while addressing current challenges in bioink formulation and bioprinting stability.

The hydrogel helps heal wounds without scars by releasing two drugs gradually.

This study developed a new suspended ointment formulation containing neomycin sulfate and triamcinolone acetonide, which showed promise for treating neurodermatitis and chronic eczema by ensuring stable composition, effective skin penetration, and no skin irritation.

This chapter reviews the hair follicle's role in drug and chemical penetration through the skin but does not present new experimental findings.

This review discusses the integration of drug repurposing with personalized medicine through off-label prescribing and reports no new results, highlighting the potential for systematic exploration using omics technologies.

This study found that male pattern hair loss worsened significantly after stopping finasteride, revealing a "rebound effect" where terminal hair transformed into miniaturized hair over 30 months off the drug.