32 citations
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June 2003 in “The American Journal of Dermatopathology” This report describes the third known case of lipedematous scalp in a 51-year-old woman, marked by progressive thickening of the scalp without hair loss, and notes its association with early meningitis symptoms.
2 citations
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January 2022 in “Lasers in Medical Science” This pilot study reported significant improvement in hair restoration and patient satisfaction with the use of fractional carbon dioxide laser followed by platelet-rich plasma, showing greater hair density increases using higher laser pulse energy settings in individuals with androgenetic alopecia.
October 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study evaluated the effects of platelet-rich plasma (PRP) on endometriosis but found no statistically significant overall difference in endometriotic foci size reduction between treated and control groups.
36 citations
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May 2005 in “BMC dermatology” This study found that topical diphenylcyclopropenone was effective in treating severe alopecia areata but had a high relapse rate and was often accompanied by side effects like eczema and lymphadenopathy.
August 2023 in “Journal of Dermatological Science” A specific RNA molecule blocks hair growth by affecting a protein related to hair loss conditions.
June 2003 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” GLABRA2 represses root hair formation by inhibiting a specific gene.
February 2025 in “Drug Delivery and Translational Research”
January 2025 in “Cellular and Molecular Biology” This study found that in Liaoning cashmere goats, overexpression of the PIP5K1A gene enhances skin fibroblast proliferation, while interference with this gene reverses melatonin-induced proliferation, and PIP5K1A regulates certain miRNA expressions, suggesting a role in improving cashmere yield and quality.
38 citations
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January 2017 in “PPAR Research” This review discusses the role of PPAR-γ in the pathogenesis of primary cicatricial alopecia, including its involvement in lichen planopilaris and treatment trials using PPAR-agonists, and reports no new clinical results.
January 2022 in “Journal of Cosmetic Dermatology” This study found that PRP injections, prepared using a digital centrifuge with a large-sized sodium citrate tube at low centrifugation speed, significantly improved hair thickness and terminal hair percentage in women with pattern hair loss, with similar results across different preparation methods.
June 2026 in “British Journal of Dermatology” This case study suggests that intense inflammation after photodynamic therapy may trigger or worsen fibrosing alopecia in susceptible individuals.
April 2016 in “Journal of Investigative Dermatology” In this study, ALP knockdown significantly impaired the hair follicle-inducing capacity of human dermal papilla spheres, highlighting a critical role for ALP in hair follicle neogenesis.
30 citations
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January 2020 in “Journal of The American Academy of Dermatology” This review reports no new clinical results but discusses fibrosing alopecia in a pattern distribution as a distinct scarring alopecia with characteristics of both androgenetic alopecia and lichen planopilaris.
January 2020 in “International Journal of Trichology” This study reported that platelet-rich plasma injections led to only temporary improvement in vellus hair characteristics in temporal triangular alopecia, suggesting it may not be an effective long-term treatment.
July 2022 in “JEADV Clinical Practice” This review discusses the classification of lichen planopilaris and its subtypes under the proposed term "lichenoid alopecias," suggesting they exist along a clinical and histological spectrum.
37 citations
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January 1986 in “Carcinogenesis” This study found that TPA treatment transiently induces high levels of ODC in mouse epidermal cells, particularly around hair follicles, with localization reduced by retinoic acid or cycloheximide pretreatment.
This study found that Fructus Ligustri Lucidi water extract significantly increased proliferation in human hair dermal papilla cells, potentially promoting hair growth by activating ERK and Akt pathways.
April 2016 in “Journal of Investigative Dermatology” This study found that full thickness wounds in Lanyu pigs led to altered molecular expression and abnormal skin structure, without regenerating key epithelial cells thought to aid in skin regeneration.
January 2012 in “Human health handbooks” This review discusses the application of low-level light therapy for hair loss treatment, particularly androgenetic alopecia, and reports no new clinical results; the authors suggest consideration of light source characteristics and potential pros and cons.
January 1998 in “Lasers in Surgery and Medicine” This study found that both 5-ALA and Photofrin can effectively destroy human microvascular endothelial cells in vitro and cause tissue necrosis in vivo, with Photofrin showing greater efficacy at lower concentrations or power densities.
16 citations
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January 2023 in “Regenerative Biomaterials” This study examined 3D-printed scaffolds coated with polydopamine and observed that they significantly enhanced osteogenesis and angiogenesis in vitro and in a rat cranium defect model, suggesting their potential for repairing large bone defects.
23 citations
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November 2017 in “Stem cell investigation” This study found that platelet lysate produced higher follicular regeneration in hair restoration surgeries compared to activated PRP and saline, with significant gains in both follicular unit and hair density.
April 2016 in “Journal of Investigative Dermatology” This study found that Pdgfα signaling is crucial for maintaining dermal adipose tissue in mice by initiating dermal adipocyte stem cell proliferation, with implications for age-related skin defects.
10 citations
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June 2018 in “Journal of visualized experiments” This study demonstrated that lactate dehydrogenase activity is notably high in quiescent hair follicle stem cells within mouse skin using a specific enzymatic activity assay.
1 citations
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September 2020 in “Journal of Dermatological Science” In this study, researchers found that the gene LRRC15 was overexpressed in dermal papilla cells from balding areas compared to non-balding areas in patients with androgenetic alopecia.
26 citations
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May 2016 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that mice lacking sPLA2-IIE had distinct skin abnormalities, particularly affecting hair follicles, highlighting the differing roles of sPLA2 isoforms in mouse skin.
September 2024 in “Dermatologica Sinica” This study reported a rare case of pityriasis rubra pilaris-like skin reaction in an 18-year-old woman after starting ponatinib treatment for relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia, which resolved after treatment adjustment and did not recur over 15 months.
7 citations
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January 2025 in “Journal of Experimental & Clinical Cancer Research” This study found that PRMT5 inhibitors showed potent anti-tumor activity in models of adenoid cystic carcinoma and that combining these inhibitors with lenvatinib may have additional growth-inhibitory effects.
1 citations
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May 2018 in “Tropical Journal of Pharmaceutical Research” This study found that low-fluence intense pulsed light promoted hair growth in C57BL/6 mice by inducing an earlier and prolonged anagen phase and activating the WNT/β-catenin pathway.
19 citations
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May 2009 in “Pediatric Dermatology” This case report describes a 5-year-old girl with childhood discoid lupus erythematosus, where treatment led to reversal of scarring alopecia and hair regrowth.