PRMT5 Inhibition Has a Potent Anti-Tumor Activity Against Adenoid Cystic Carcinoma of Salivary Glands

    January 2025 in “ Journal of Experimental & Clinical Cancer Research ”
    Vasudha Mishra, Alka Singh, Michael Korzinkin … Evgeny Izumchenko
    Studysummary This study found that PRMT5 inhibitors showed potent anti-tumor activity in models of adenoid cystic carcinoma and that combining these inhibitors with lenvatinib may have additional growth-inhibitory effects.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on jeccr.biomedcentral.com →
    Discuss this study in the Community →

    Research cited in this study 3

    1. Identification of Dual-Purpose Therapeutic Targets Implicated in Aging and Glioblastoma Multiforme Using PandaOmics - An AI-Enabled Biological Target Discovery Platform Aging · 2023
    2. High-Confidence Cancer Patient Stratification Through Multiomics Investigation of DNA Repair Disorders Cell Death and Disease · 2022
    3. An Analysis of Gene Expression Data Involving Examination of Signaling Pathways Activation Reveals New Insights into the Mechanism of Action of Minoxidil Topical Foam in Men with Androgenetic Alopecia Cell Cycle · 2017