4 citations
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September 2012 in “Clinical Pharmacology in Drug Development” This study reviewed the dosages of products approved in Japan from 2003-2010 and found that 28.1% were at different levels than in the U.S., with limited evidence suggesting different clinical responses.
4 citations
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December 2011 in “Journal of The American Academy of Dermatology” This study found that higher cumulative doses of topical minoxidil solution were strongly associated with improved hair density and thickness in male patients with androgenic alopecia over a 24-week period.
4 citations
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November 1981 in “Indian Journal of Dermatology Venereology and Leprology” This study observed that oral calcium pantothenate may reverse hair greying in some adolescent cases, as seen in two girls whose grey hairs turned black after treatment.
4 citations
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July 2019 in “Headache The Journal of Head and Face Pain” This study suggests that low alternating daily doses of sodium divalproate may be effective for migraine prevention, similarly to higher doses, but can still lead to modest weight gain.
3 citations
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May 2016 in “Gynecological Endocrinology” This study found that while flutamide was very effective in improving hirsutism in women over long-term treatment, a high incidence of adverse effects led to a majority discontinuing the therapy.
3 citations
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December 2015 in “Musculoskeletal care” This study found that many patients taking methotrexate for inflammatory arthritis tolerate significant side effects, but adherence to the medication still varies among individuals.
3 citations
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April 1977 in “PubMed” In this study, patients with varying severities of acne, seborrhoea, and hirsutism responded differently to Cyproteronacetate and Ethinyloestradiol treatment, with improvement rates dependent on symptom severity and treatment duration.
2 citations
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August 2024 in “Molecular Genetics & Genomic Medicine” In this case study, an 8-day-old neonate with holocarboxylase synthetase deficiency showed dramatic improvement in lactic acidosis and overall clinical condition following biotin mega-dose therapy, highlighting the importance of early genetic testing and timely treatment in such metabolic disorders.
2 citations
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March 2022 in “Laboratory Animal Research” This study suggests that a mild intramuscular dose of botulinum toxin improved spermatogenesis and sperm parameters in ageing mice.
2 citations
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March 2021 in “Journal of Cosmetic Dermatology” This pilot study found that among male androgenetic alopecia patients, 2.5 mg oral minoxidil with platelet-rich plasma led to higher patient satisfaction than 1.25 mg, though hair count improvements were not statistically significant.
This study found that a single dose of PRP with 100 billion platelets significantly reduced pain and improved knee function in patients with osteoarthritis, but did not alter joint structure on MRI.
2 citations
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June 2016 in “Journal of Korean Medicine” This study found that low concentrations of Asiasarum heterotropoides extract may enhance proliferation of human mesenchymal stem cells from periodontal tissue without affecting cell morphology.
2 citations
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January 2014 in “Chinese medicine” This study found that the polyherbal cough syrup Linkus reduced cough reflexes without causing observed toxicity in rats, suggesting it may be an effective and safe option.
2 citations
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January 2015 in “Journal of Investigative Dermatology” 1 citations
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November 2022 in “International journal of molecular sciences” This study found that local injections of fetal tissue mesenchymal stromal cells in mice significantly improved healing and hair follicle density after high-dose radiation-induced skin damage.
1 citations
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May 2021 in “Thyroid Research and Practice” This study found that low-dose radioactive iodine therapy for hyperthyroidism and thyroid cancer produced short-term adverse effects like loss of taste, xerostomia, and hair loss, which were self-limiting.
1 citations
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July 2017 in “The Journal of Urology” In this study, low dose finasteride or dutasteride treatment was found to reduce prostate specific antigen levels in men with androgenetic alopecia, though levels sometimes remained stable or increased in those with low baseline PSA.
1 citations
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January 2007 in “The Kitakanto Medical Journal” This report documents a case where a man survived sub-acute toxicity from an overdose of the anticancer drug UFT due to effective treatment with antibiotics and granulocyte colony-stimulating factor.
1 citations
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January 2004 This study found that low-dose intermittent corticosteroid therapy may be a successful and well-tolerated treatment option for patients with alopecia areata, including those with alopecia totalis and universalis.
July 2026 in “Dermatology Practical & Conceptual” In this study, the researchers observed that gastrointestinal side effects, such as flatulence and abdominal discomfort, were more common in patients taking low-dose oral minoxidil, especially among males and those using concurrent vasodilators.
July 2026 in “British Journal of Dermatology” This study observed that administering low-dose oral minoxidil during the daytime led to significantly greater hair density improvements in androgenetic alopecia patients compared to nighttime dosing. This suggests that circadian variations in hair follicle biology could be important for optimizing treatment outcomes.
April 2026 in “Almanac of Clinical Medicine” In this study, pemphigus vulgaris patients treated with high-dose prednisolone developed symptoms similar to those seen in corticosteroma, such as weight gain and muscle weakness, with increased risks of arterial hypertension and glucose metabolism disorders after 6 months of therapy.
April 2026 in “Journal of the American Academy of Dermatology”
March 2026 in “Journal of Pakistan Association of Dermatologists” This study found that low-dose oral minoxidil was more effective than topical minoxidil in increasing hair density and patient satisfaction among men with androgenetic alopecia, with fewer local side effects and better compliance reported over six months.
July 2025 in “International Journal of Homoeopathic Sciences” This article reports on a case where a patient with alopecia areata experienced significant hair regrowth and psychological improvement after four months of treatment with a single individualized dose of the homeopathic remedy Natrum muriaticum.
June 2025 in “British Journal of Dermatology” In this study, a daily low-dose regimen of oral minoxidil and finasteride over 12 months led to significant hair density improvements in over 92% of adult men with androgenetic alopecia, including those with advanced stages, though inter-rater reliability in photo assessments was modest.
May 2025 in “International Journal of Trichology” This prospective study reported that 5 mg daily oral low-dose minoxidil over 24 weeks led to a high prevalence of hypertrichosis in 93% of male androgenetic alopecia patients, particularly affecting younger individuals, but generally had minimal impact on patients’ quality of life.
January 2025 in “The Journal of Dermatology” This study found that patients with severe alopecia areata are willing to accept increased risks of serious infection, cancer, and blood clots when opting for a higher dose of ritlecitinib, valuing the potential for greater hair regrowth efficacy compared to a lower dose.
January 2025 in “Annals of Dermatology” In this study, 0.2 mg dutasteride significantly improved hair growth in men with androgenetic alopecia compared to placebo over 24 weeks, showing similar efficacy to the higher 0.5 mg dose with a favorable safety profile.
December 2024 in “Frontiers in Neurology” In this pilot randomized clinical trial, TRT combined with finasteride increased lean mass, muscle size, and bone mineral density without prostate enlargement in men with spinal cord injury, suggesting potential benefits for body composition and musculoskeletal health.