Pharmacological Efficacy of Low-Dose Oral Minoxidil–Finasteride Combination for Hair Growth and Stability in Male Androgenetic Alopecia: A 12-Month Retrospective Service Evaluation

This study evaluated the effectiveness of a daily oral regimen combining low-dose minoxidil (2.5 mg) and finasteride (1 mg) over 12 months in 502 men with androgenetic alopecia. Results showed that 92.4% of participants were stable or improved, with 57.4% experiencing noticeable hair regrowth. The mean seven-point change in hair density was 0.58, indicating a statistically significant increase. Effect sizes varied from moderate in early hair loss stages to large in severe cases, with Norwood 5–6 showing the most significant improvements. Despite subjective variability in assessments, the combination treatment demonstrated robust efficacy across different severities of hair loss. Future research should focus on objective imaging and safety monitoring to optimize treatment protocols.