Pharmacological Efficacy of Low-Dose Oral Minoxidil–Finasteride Combination for Hair Growth and Stability in Male Androgenetic Alopecia: A 12-Month Retrospective Service Evaluation

This study evaluated the effectiveness of a daily oral minoxidil (2.5 mg) and finasteride (1 mg) regimen over 12 months in 502 men with androgenetic alopecia (AA). Results showed that 92.4% of participants were stable or improved, with 57.4% experiencing noticeable hair regrowth. The mean seven-point change in hair density was 0.58, indicating a statistically significant increase. Effect sizes varied, being moderate in early hair loss stages (Norwood 2–3) and large in more severe stages (Norwood 5–6). Despite subjective variability in assessments, the treatment demonstrated robust improvements across different severities of AA. The study suggests the need for objective imaging protocols in future research and highlights the potential of this combination therapy for treating AA.