Pattern of Short-Term Adverse Effects in Patients Undergoing Low-Dose Radioactive Iodine Therapy

    Ancy George, Y. Annapurna, P. Harilal, Anila Kumari Vatakke Purayil
    TLDR Short-term side effects of low-dose radioactive iodine therapy are common but temporary.
    The study examined short-term adverse effects of low-dose radioactive iodine therapy in 53 patients with hyperthyroidism and differentiated thyroid carcinoma. Common adverse effects included loss of taste and smell (39%), xerostomia (32%), and hair loss (26%), with hair loss being more prevalent in females. No significant link was found between adverse effects and age, gender, or dose. Blood tests revealed a significant decrease in platelet count and lymphocytes post-therapy. Despite the commonality of adverse effects, they were generally mild and manageable, leading to the conclusion that low-dose RAIT was a safe and noninvasive procedure, though monitoring adverse effects was important to reduce patient discomfort.
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