9 citations
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January 2021 in “Acta Cirúrgica Brasileira” This study found that DPG promoted wound healing in rat skin, with increased collagen I density, particularly evident within the first 14 days after injury.
August 2018 in “Journal of Investigative Dermatology” This case report describes the first known instance of dermatomyositis-related panniculitis in the neck and mediastinal region, effectively treated with corticosteroids, dapsone, and colchicine.
488 citations
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July 2021 in “Cell” This review discusses the development, lineages, functions, and roles of fibroblasts in fibrosis across four organs, highlighting their capabilities in tissue repair and contributions to fibrotic disorders when aberrantly activated, but it reports no new experimental findings.
March 2019 in “SLAS TECHNOLOGY” This study found that MSN-ceria nanomaterial accelerates cutaneous wound healing in rat models by reducing ROS levels and promoting collagen deposition, leading to improved tissue regeneration without significant scarring.
October 2022 in “Frontiers in Bioengineering and Biotechnology” This study demonstrated that in a mouse model of androgenic alopecia, PLGA-DUT/siAR@DPCM nanoparticles effectively delivered drugs to hair follicles, suppressed androgen-related targets, promoted cell proliferation, and showed significant therapeutic effects with minimal adverse effects, suggesting their potential for clinical application.
September 2025 in “Development” In this study, deleting the transcriptional pause factor Nelfb in mouse preadipocyte lineages led to defective dermal fat formation and lethal outcomes, while interventions targeting Pparg could rescue adipocyte differentiation and promote dermal white adipose tissue formation, underscoring Nelfb's critical role in adipogenesis.
February 2023 in “Medicine in novel technology and devices” This study found that microneedle delivery of Polygonum multiflorum extract led to earlier pigmentation and hair regrowth in mice with androgenetic alopecia.
8 citations
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January 2023 in “Skin Research and Technology” This study found that treatment with fractional 1064 nm picosecond Nd:YAG laser effectively reduced post-acne erythema in adult Chinese patients without causing scarring or pigmentation issues, though some experienced temporary erythema, oedema, pruritus, and acne eruptions.
110 citations
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January 2014 in “Journal of Controlled Release” Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This study reported that combining Poly-D,L-Lactic Acid with Platelet-Rich Plasma for facial rejuvenation reduced wrinkle severity and improved skin tone and hyperpigmentation in a 45-year-old female patient.
June 2026 in “Journal of Cosmetic Dermatology” PDRN may help with female hair loss, but more research is needed.
8 citations
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June 2021 in “Frontiers in Medicine” This study reported that the combination of a 308-nm excimer lamp and 10% liquor carbonis detergens significantly improved scalp psoriasis symptoms compared to the excimer lamp alone, with more patients achieving 75% reduction in their Psoriasis Scalp Severity Index.
1 citations
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January 2004 in “Cosmetics and toiletries” Polyquaternium-64 helps damaged hair look healthy again.
February 2025 in “Archives of Dermatological Research” Polynucleotides effectively promote hair regrowth in androgenetic alopecia without serious side effects.
11 citations
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September 2010 in “PubMed” In this study, the researchers compared the pharmacokinetics and tissue distribution of dihydroartemisinin in nanostructured lipid carriers versus in solution, finding longer mean residence times and variable organ accumulation with the nanostructured lipid carriers.
March 2026 in “ACS Applied Materials & Interfaces” This study described a novel three-dimensional-printed microneedle system designed for improved transdermal delivery of minoxidil to treat hair loss, demonstrating effective hair regrowth and safety in a mouse model while allowing sustainable needle base recovery.
January 2012 in “RepositóriUM (Universidade do Minho)” This study reported that a modified nanoprecipitation protocol can effectively create PLA nanoparticles capable of delivering compounds into hair follicles, with promising potential for hair follicle therapy and cosmetic applications.
July 2024 in “Journal of Investigative Dermatology” In these two clinical trials, DS-2325a, a KLK5 inhibitor, was found to be generally safe and well tolerated in healthy volunteers, with mild and non-serious adverse events, suggesting its potential for further development as a treatment for Netherton Syndrome.
August 2023 in “MPPKI (Media Publikasi Promosi Kesehatan Indonesia) : The Indonesia journal of health promotion” In this study, researchers used a UV-Vis Spectrophotometer to qualitatively and quantitatively analyze Dutasteride residues in human plasma, achieving a total recovery rate of 64.992%, and determined that the BTB reagent effectively selected compounds not analyzed in their research.
The research found that while Dnmt3a and Dnmt3b are not necessary for skin homeostasis in mice, the loss of Dnmt3a increases squamous tumor formation from carcinogens, and combined deletion of both results in more aggressive and metastatic tumors.
January 2022 in “Clinical Cases in Dermatology” This case report describes a middle-aged man with niacinamide-induced poikilodermatous flushing observed on the neck, established through clinical and dermatoscopic evaluation.
18 citations
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January 2018 in “International journal of medical sciences” This study found that non-thermal plasma treatment increased epidermal thickness and dermal collagen density in mouse skin tissue without causing damage, potentially promoting growth factors and tissue remodeling.
February 2024 in “International Journal For Multidisciplinary Research” This review examines the advances in nanostructured lipid carriers for treating hyperpigmentation but presents no new clinical results; the authors highlight their potential benefits and applications.
October 2022 in “International journal of medical science and clinical research studies” In this study, the combination of Poly-D,L-Lactic Acid and Platelet-Rich Plasma was reported to be effective for improving wrinkle severity and skin brightness in a 45-year-old woman.
50 citations
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December 2017 in “Nanoscale” This study found that polymeric micelle formulations significantly improved the targeted delivery of adapalene to hair follicles compared to standard Differin® products, which suggests potential advantages in treating hair follicle-related conditions and reducing side effects.
November 2023 in “Journal of cosmetic dermatology” This report describes three cases of erythromelanosis follicularis faciei et colli showing significant improvement in facial telangiectasia following treatment with a 595-nm pulsed dye laser, with minimal recurrence observed during follow-up.
6 citations
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December 2024 in “International Journal of Biological Macromolecules” This study introduced a novel exosome-loaded sprayable hydrogel (ADA-aPF127@LL18/Exo) that significantly enhanced wound healing in a deep partial thickness burn model, showing improved antibacterial efficacy and promoting tissue recovery processes like epithelialization and hair follicle regeneration.
2 citations
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January 2023 in “Ceramics International” In this study, the Cu-doped bioglass composite dressings showed promising results for wound healing and hair follicle regeneration in vitro, with enhanced fibroblast proliferation and vascular growth.
May 2005 in “Molecular Carcinogenesis” This study found that mrp/plf-mRNA expression in murine skin increases in response to different tumor promoters, suggesting its potential as a short-term biomarker for chemical carcinogenesis.
April 2026 in “Frontiers in Medicine” This study observed that 675-nm diode laser therapy may serve as a safe and possibly effective adjuvant treatment for telogen effluvium, showing improvements in hair pull test results, pruritus, and trichodynia among patients. However, controlled studies are needed to confirm its efficacy.