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This study found that a microenvironment-responsive ATAN-Met hydrogel system improved infective diabetic wound healing by enhancing re-epithelialization, neurovascular and hair follicle regeneration, and exhibited antibacterial and immunoregulatory effects, activated beneficial pathways, and responded to glucose/ROS for drug release.

Platelet-rich plasma with microneedling is effective for hair loss, but the number of sessions needed varies.

This study reported that a composite hydrogel made with Chlorella-derived extracellular polysaccharide–selenium nanoparticles showed strong antibacterial and anti-inflammatory effects in vitro and significantly accelerated wound healing in vivo, offering potential for managing infected wounds and monitoring healing progression.

This study concluded that an adapalene nanohydrogel containing Tween-80 could be a promising and stable topical treatment option for acne vulgaris due to enhanced skin permeability and stability compared to other formulations.

This study found that finasteride-loaded microemulsions using poloxamer 124 significantly enhanced skin penetration of the drug compared to a standard solution, primarily through targeting hair follicles via the transfollicular pathway, with intercluster, intercellular, and transcellular pathways contributing less.

This study found that applying controlled hypobaric stress to the skin significantly improved the in vitro and in vivo penetration of macromolecules, facilitating enhanced drug delivery.

This study observed that both intralesional triamcinolone acetonide and microneedling with triamcinolone acetonide significantly reduced alopecia areata severity, with no significant difference in effectiveness between the two treatments, suggesting microneedling as an effective and less invasive option.

This study developed a new suspended ointment formulation containing neomycin sulfate and triamcinolone acetonide, which showed promise for treating neurodermatitis and chronic eczema by ensuring stable composition, effective skin penetration, and no skin irritation.

In this study, a chronotherapeutic bilayer dressing system showed enhanced diabetic wound healing in a model by reducing inflammation through polyphenols and promoting repair with sustained PDGF-BB delivery, leading to faster re-epithelialization and hair follicle regeneration.

This study found that transethosomal gel loaded with propranolol hydrochloride prolonged drug release and increased peak plasma concentration compared to an oral tablet, suggesting a promising alternative for delivery.

This study found that nanodiamonds of various sizes can penetrate different layers of murine skin in vitro, reaching hair follicle niches, and may be suitable for multimodal imaging applications.

This study found that using a PEG-400/oleic acid mixture as an optical clearing agent enhanced the detection depth of particles in skin without causing dehydration, based on tests in rats and further testing in vivo.

This article discusses a novel device for applying mediums to human and animal tissues and reports no new clinical results, focusing on its potential for precise applications and enhanced cell transplants.

In this study, an innovative composite hydrogel incorporating methylene blue-loaded nanoparticles was developed for 3D-printed wound dressings, showing improved mechanical properties, excellent antibacterial effects, and enhanced skin healing in mice.

Liposomes with certain properties can effectively deliver drugs deep into hair follicles.

In this study, nanoemulsion formulations were found to significantly enhance the skin retention of the antiseptic agent triclosan, with the optimal mixture being a low surfactant concentration, as demonstrated through quantitative and qualitative analysis using tape-stripping and micro CT scans.

In this study, researchers developed a versatile sprayable hydrogel that promotes wound healing in mice by facilitating rapid gelation, reducing inflammation, and accelerating tissue regeneration, with potential applications in chronic wound treatment and beyond.

This study developed a peptide-based topical delivery system that enhanced hair growth with reduced systemic exposure to finasteride, showing efficacy comparable to 5% minoxidil in vivo while using significantly less finasteride than oral doses.

In this study, microneedling and intralesional corticosteroid injections in patients with alopecia areata showed similar hair regrowth effectiveness, with microneedling resulting in more uniform but less dense regrowth and fewer side effects.

This study suggests that MultiDomain Peptide hydrogels may support wound healing in diabetic mice by accelerating closure and promoting tissue regeneration, though they did not inhibit bacterial growth in infected wounds as expected.

This study found that a nanoparticle-in-nanofiber system significantly accelerated wound healing in rats by promoting angiogenesis and tissue regeneration more effectively than a commercial wound dressing.

Results are not reported in this abstract, but it outlines the objective to evaluate the efficacy of microneedling, alone and in combination with other treatments, for pattern hair loss through a systematic review and meta-analysis.

This study used novel methods to detect and map iodine concentrations in pig skin, finding iodine present in the coating, stratum corneum, and tissue around hair follicles.

This review discusses the potential of topical nanoemulsions to transform skin cancer treatment by improving drug delivery and minimizing side effects, highlighting their advantages like enhanced skin permeation and controlled release, despite existing challenges.

This study found that the cyanoacrylate biopsy method could effectively evaluate drug distribution in hair follicles, suggesting its potential utility for assessing topically applied chemicals targeting hair follicles.

This study found that microneedling with longer needles (3 mm) showed better hair regrowth in dogs with hair cycle arrest, although most experienced recurrent hair loss during follow-up. Some dogs also developed minor, temporary itching.

In this study, radiofrequency microporation significantly improved topical minoxidil delivery and hair regrowth in a mouse model of androgenetic alopecia, with minimal systemic exposure compared to oral administration, suggesting it could be a promising needle-free option for topical therapy.

This study introduces a novel pro-drug formulation of all-trans retinoic acid that reduces skin inflammation and achieves sustained drug release over several days compared to traditional methods.

This study developed and tested nanostructured lipid carriers for topical dutasteride delivery, finding them stable, low in cytotoxicity and non-irritating, with no drug permeation through pig ear skin over 48 hours.

In this study, formulations containing 20% zinc oxide nanoparticles demonstrated stability and improved spreadability without penetrating the deepest skin layers, instead accumulating in skin furrows and hair follicles.