9 citations
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October 2021 in “Journal of Cosmetic Dermatology” This study found that microneedling monotherapy significantly increased hair count more than topical minoxidil in androgenetic alopecia, with combination therapy of microneedling and minoxidil being even more effective. Further research is needed to evaluate microneedling's safety and efficacy as a monotherapy.
2 citations
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December 2019 in “Veterinary Dermatology” This study found that in dogs with post-clipping alopecia, microneedling with platelet-rich plasma may induce more rapid hair regrowth compared to microneedling alone, though results were similar by six months.
18 citations
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October 2017 in “PLOS ONE” This study found that in Pomeranians with Alopecia X, key genes in the Wnt and Shh signaling pathways and stem cell markers are downregulated, which may explain the absence of anagen hair follicles.
49 citations
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August 2016 in “Aesthetic Surgery Journal” This study found that micro-needling with cosmeceuticals or platelet-rich plasma significantly improved wrinkles, skin laxity, scar softening, and hair growth over 12 months, with minimal side effects, and that the best results occur with pigment and platelet massaging between 5 to 30 minutes post-treatment.
55 citations
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January 2016 in “Annals of Dermatology” This study found that repeated microneedle stimulation in mice promoted hair growth and increased the expression of hair-growth-related genes, suggesting potential therapeutic uses for alopecia.
12 citations
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July 2015 in “Veterinary Dermatology” This study observed that microneedling induced significant hair regrowth and reduced hyperpigmentation in two Pomeranians with alopecia X, with stable results over 12 months.
22 citations
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September 2014 in “Veterinary Dermatology” This study found that low-level laser therapy may have promising effects on hair regrowth in dogs with noninflammatory alopecia, with most animals showing improvement after treatment.
10 citations
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July 2014 in “Veterinary dermatology” This study found that deslorelin may promote hair regrowth in intact male dogs with hair cycle arrest, but had no effect on neutered females.
10 citations
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September 2013 in “Veterinary dermatology” This study found that medroxyprogesterone injections led to partial or complete hair regrowth in some Pomeranian dogs with alopecia X, though their IGF-1 levels remained unchanged.
136 citations
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January 2013 in “International Journal of Trichology” This study found that adding microneedling to minoxidil treatment significantly improved hair growth in men with androgenetic alopecia compared to minoxidil alone across all assessed measures.
207 citations
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March 2012 in “Development” In this mouse study, researchers found that dermal Wnt signaling/β-catenin activity is essential for fibroblast proliferation and initiating hair follicle formation by interacting with epidermal Wnt ligands.
759 citations
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February 2009 in “Current Biology” This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.
40 citations
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October 2004 in “Veterinary Dermatology” In this study, trilostane treatment led to complete hair re-growth in 85% of Pomeranians and all miniature poodles with alopecia X within 4 to 8 weeks.
52 citations
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October 2004 in “Veterinary dermatology” This study found that 62% of neutered dogs with hair cycle arrest experienced partial to complete hair re-growth after melatonin treatment, but hair re-growth was not consistently linked to normal sex hormone levels.