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Human skin has less GDNF and its receptor with age.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Finasteride may affect PNMT, causing side effects.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Keratin filaments' elasticity is influenced by their terminal domains and surrounding medium.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

3D-cultured cells in HGC-coated environments improve hair growth and skin integration.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Where melanoma is on the body affects survival chances; melanomas on the back of the head are worse, while those on thighs and arms are less severe, and more sun exposure might improve survival.

Human pluripotent stem cells could be used to make platelets for medical use, but safety, effectiveness, and cost issues need to be resolved.

Permanent hair dyes use chemicals that react with hydrogen peroxide to create color.

Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Healthy scalp leads to better hair quality and less damage.

PRP helps skin regeneration but needs standardized testing for consistent results.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

The document concludes that a Quality Management System is crucial for maintaining product quality through innovation and proper technology transfer in the pharmaceutical industry.

Caffeine improves hair growth, thickness, and reduces shedding.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Different types of skin cells play specific roles in development, healing, and cancer.