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    Glossary Diphenylcyclopropenone

    topical immunotherapy agent used to treat alopecia areata

    Diphenylcyclopropenone (DPCP) is a topical immunotherapy agent used primarily to treat alopecia areata, a condition that causes hair loss. It works by inducing a mild allergic reaction on the scalp, which is thought to distract the immune system from attacking hair follicles, thereby promoting hair regrowth.

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    1. Efficacy and safety of diphenylcyclopropenone alone or in combination with anthralin in the treatment of chronic extensive alopecia areata: A retrospective case series Journal of the American Academy of Dermatology · 2015 · 44 citations
    2. Clinical Efficacy of Diphenylcyclopropenone in Alopecia Areata: Retrospective Data Analysis of 50 Patients 2015 · 41 citations
    3. Topical immunotherapy of severe alopecia areata with diphenylcyclopropenone (DPCP): experience in an Iranian population BMC dermatology · 2005 · 36 citations
    4. Systematic review and quality analysis of studies on the efficacy of topical diphenylcyclopropenone treatment for alopecia areata Journal of The American Academy of Dermatology · 2017 · 21 citations
    5. Efficacy and safety of anthralin in combination with diphenylcyclopropenone in the treatment of alopecia areata: a retrospective case series Archives of dermatological research · 2019 · 20 citations
    6. Diphenylcyclopropenone in patients with alopecia areata. A critically appraised topic British Journal of Dermatology · 2015 · 19 citations
    7. Videocapillaroscopic Pattern of Alopecia Areata before and after Diphenylciclopropenone Treatment International Journal of Immunopathology and Pharmacology · 2011 · 17 citations
    8. Severe dermographism after topical therapy with diphenylcyclopropenone for alopecia universalis Contact dermatitis · 2000 · 16 citations
    9. Alopecia areata in a Patient with Candidiasis-Endocrinopathy Syndrome: Unsuccessful Treatment Trial with Diphenylcyclopropenone Dermatology · 1995 · 16 citations
    10. Clinical efficacy of diphenylcyclopropenone in alopecia areata: Retrospective data analysis of 50 patients Journal of the American Academy of Dermatology · 2014 · 14 citations
    11. Treatment of chronic extensive alopecia areata by diphenylcyclopropenone alone versus in combination with anthralin Dermatologic therapy · 2019 · 10 citations
    12. Efficacy of diphenylcyclopropenone in alopecia areata: a comparison of two treatment regimens Postępy Dermatologii i Alergologii · 2018 · 10 citations
    13. Phototherapy as a Useful Therapeutic Option in the Treatment of Diphenylcyclopropenone-induced Vitiligo Acta dermato-venereologica · 2010 · 10 citations
    14. Possible advantage of imiquimod and diphenylcyclopropenone combined treatment versus diphenylcyclopropenone alone: An observational study of nonresponder patients with alopecia areata Australasian journal of dermatology · 2016 · 9 citations
    15. Efficacy of topical diphenylcyclopropenone maintenance treatment for patients with alopecia areata: A retrospective study Journal of the American Academy of Dermatology · 2018 · 8 citations
    16. Extensive Scalp Angioedema following High-Dose Diphenylcyclopropenone for Alopecia Areata Hospital pharmacy · 2014 · 5 citations
    17. Diphenylcyclopropenone-Induced Vitiligo in a Patient with Alopecia Universalis Case reports in dermatology · 2013 · 4 citations
    18. Use of diphenylcyclopropenone for alopecia areata treatment during pregnancy JAAD Case Reports · 2024 · 3 citations
    19. Treatment Response to Diphenylcyclopropenone in Patients with Alopecia Totalis/Universalis International Journal of Trichology · 2023 · 3 citations
    20. Economic Impact of Home-Use versus Office-Use Diphenylcyclopropenone in Extensive Alopecia Areata Skin Appendage Disorders · 2021 · 3 citations
    21. Comparative Study between The Efficacy and Safety of Topical Immune Therapy with Diphenylcyclopropenone versus Anthralin in The Treatment of Resistant Alopecia Areata International Journal of Medical Arts · 2024 · 2 citations
    22. Diphenylcyclopropenone alleviates trachyonychia in alopecia universalis International Journal of Dermatology · 2024 · 2 citations
    23. Diphenylcyclopropenone: An Important Agent Known to Cause Depigmentation / Reply Dermatology · 1999 · 2 citations
    24. Topical Immunotherapy with Diphenylcyclopropenone in Paediatric Patients with Alopecia Areata—A Retrospective Study of 97 Patients Skin Health and Disease · 2024 · 1 citations
    25. Preparation, solubility, and anti-inflammatory effects of a complex of diphenylcyclopropenone/β-cyclodextrin derivatives as the treatment of alopecia areata Journal of Pharmacy & Pharmaceutical Sciences · 2024 · 1 citations
    26. Diphenylcyclopropenone Treatment Outcomes for Alopecia Areata Deleted Journal · 2023 · 1 citations
    27. A case report of verruca vulgaris on basis of alopecia areata successfully treated with diphenylcyclopropenone International journal of trichology · 2017 · 1 citations
    28. Randomized Controlled Trial Study to Evaluate the Efficacy of Combination Therapy with Diphenylcyclopropenone and Platelet-Rich Plasmain Alopecia Areaata International Journal of Trichology · 2025
    29. 51721 Analysis for recurrence of alopecia areata after immunotherapy with diphenylcyclopropenone in 113 patients: A single-institution retrospective analysis Journal of the American Academy of Dermatology · 2024
    30. Diphenylcyclopropenone in severe alopecia areata in children and adolescents: long-term follow-up and relapse rate Journal of the Egyptian Womenʼs Dermatologic Society · 2024