Efficacy and Safety of Anthralin in Combination with Diphenylcyclopropenone in the Treatment of Alopecia Areata: A Retrospective Case Series

    June 2019 in “ Archives of dermatological research ”
    Maryam Nasimi, Narges Ghandi, Robabeh Abedini … Sk. Sarif Hassan
    Studysummary In this study, combination therapy with DPCP and anthralin promoted hair regrowth in 40.62% of alopecia areata patients who were unresponsive to DPCP alone, with response improving over longer treatment durations.
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    Research cited in this study 15

    1. Alopecia Areata: Treatment Options and Efficacy Journal of the American Academy of Dermatology · 2017
    2. Systematic Review and Quality Analysis of Studies on the Efficacy of Topical Diphenylcyclopropenone Treatment for Alopecia Areata Journal of The American Academy of Dermatology · 2017
    3. Higher Concentrations of Dithranol Appear to Induce Hair Growth Even in Severe Alopecia Areata Dermatologic therapy · 2017
    4. Possible Advantage of Imiquimod and Diphenylcyclopropenone Combined Treatment Versus Diphenylcyclopropenone Alone: An Observational Study of Nonresponder Patients With Alopecia Areata Australasian journal of dermatology · 2016
    5. Retrospective Review of Diphencyprone in the Treatment of Alopecia Areata Clinical and Experimental Dermatology · 2015
    6. Efficacy and Safety of Diphenylcyclopropenone Alone or in Combination with Anthralin in the Treatment of Chronic Extensive Alopecia Areata: A Retrospective Case Series Journal of the American Academy of Dermatology · 2015
    7. British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012 British Journal of Dermatology · 2012
    8. Alopecia Areata Update Journal of the American Academy of Dermatology · 2010
    9. Alopecia Areata Update Journal of The American Academy of Dermatology · 2010
    10. Interventions for Alopecia Areata Cochrane library · 2008
    11. Changes in Distribution Pattern of CD8 Lymphocytes in the Scalp in Alopecia Areata During Treatment With Diphenylcyclopropenone Archives of dermatological research · 2007
    12. Restoration of Hair Growth in Mice with an Alopecia Areata-Like Disease Using Topical Anthralin Experimental Dermatology · 2004
    13. Old Wine in New Bottles: Reviving Old Therapies for Alopecia Areata Using Rodent Models Journal of Investigative Dermatology Symposium Proceedings · 2003
    14. The Therapeutic Use of Topical Contact Sensitizers in Benign Dermatoses British journal of dermatology/British journal of dermatology, Supplement · 2001
    15. Treatment of Chronic Severe Alopecia Areata with Topical Diphenylcyclopropenone and 5% Minoxidil: A Clinical and Immunopathologic Evaluation Journal of The American Academy of Dermatology · 1993

    Related research 1

    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019