Diphenylcyclopropenone and Platelet-Rich Plasma in the Management of Severe or Recalcitrant Alopecia Areata

June 2023 in “ Journal of cosmetic dermatology ”

Wafaa Mohamed Abd El‐Magid, Rouga Moumouni Mohamed, Reham Elsharkawy

Diphenylcyclopropenone platelet-rich plasma alopecia areata DPCP PRP AA

TLDR Both DPCP alone and with PRP are effective and safe for treating severe alopecia areata.

The study compared the effectiveness of Diphenylcyclopropenone (DPCP) alone versus DPCP combined with platelet-rich plasma (PRP) in treating severe or recalcitrant alopecia areata (AA) in 24 patients. Group A (13 patients) received DPCP alone, while Group B (11 patients) received both DPCP and PRP. After six months, the response rates were 53.85% for Group A and 54.5% for Group B, with no statistically significant difference between the groups. Both treatments were found to be effective and safe, though the study suggested the need for larger sample sizes and longer treatment durations in future research. No serious complications were reported.

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18 / 18 results

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