TLDR Diphenylcyclopropenone (DPCP) effectively treated both alopecia areata and verruca vulgaris.
A 23-year-old male with alopecia areata and periungual verruca vulgaris was treated with diphenylcyclopropenone (DPCP) after initial treatments with corticosteroids, minoxidil, and 5-fluorouracil were halted due to viral wart contamination on the scalp. DPCP application led to the disappearance of hyperkeratotic papules and subsequent hair regrowth after 17 applications, though it was less effective for periungual warts, which required additional cryotherapy and intralesional bleomycin. This case highlighted the potential efficacy of DPCP for treating both conditions, despite it not being a first-line therapy.
71 citations,
December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” There are no FDA-approved treatments for Alopecia Areata, and current options have varying success and relapse rates.
110 citations,
December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.
60 citations,
September 2001 in “British journal of dermatology/British journal of dermatology, Supplement” Topical contact sensitizers can treat certain skin conditions by changing the immune response.
July 2018 in “British Journal of Dermatology” Hair regrowth was seen in 83% of children with alopecia, immune system plays a role in the condition, and various treatments showed effectiveness for hair and nail disorders.
59 citations,
September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
The document is a detailed guide on skin conditions and treatments for dermatologists.
September 2022 in “Dermatology and therapy” Contact immunotherapy might help treat various skin conditions, but more research is needed to confirm its safety and effectiveness.
4 citations,
August 2013 in “Case reports in dermatology” A patient with total hair loss developed vitiligo after using a treatment called DCP.
