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Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.

COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Hormonal therapy like cyproterone acetate and spironolactone may help female hair loss, but more research is needed, especially for pre-menopausal women.

Three natural compounds from Ghanaian plants may help treat BPH and alopecia.

Obesity and bariatric surgery can cause hair thinning and temporary hair loss due to nutritional deficiencies and stress.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

New understanding and treatments for hair loss are improving, but more research is needed.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

Topical minoxidil is the best-supported treatment for female hair loss, but personalized plans are needed.

The Trust tonic is more effective than minoxidil for treating hair loss.

Finasteride worsens heart damage from nandrolone decanoate but protects against cell damage.

Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.

The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.

Androgens and estrogens are crucial for insulin secretion in males.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Both drugs lower DHT levels, with GI198745 being more effective.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.

DHT stops hair regrowth in mice, similar to human hair loss.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Researchers created a cell line to study hair growth and found specific genes affected by dihydrotestosterone.

The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.