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This study analyzed the lipid composition of mouse hair, focusing on sphingolipids, and found significant differences in ceramides, glucosylceramides, and sphingomyelins between hair follicles and hair shafts.

This study suggests that decreased levels of dihydroceramide in hair may serve as a biomarker for the progression of alopecia.

This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.

This study found that the distribution of desmogleins is associated with specific types of keratinization and hair anchorage, as well as hypotrichosis.

In this study, the researchers found that deleting ceramide synthase 4 in the skin's epidermis alters stem cell differentiation, disrupting hair follicle structure and barrier function, potentially leading to immune responses similar to atopic dermatitis.

This study found that sphinganine may improve scalp health, hair quality, and reduce hair loss in males, potentially due to increased antimicrobial peptide levels and inhibition of 5-α-reductase.

This study found that applying a 1% BOI lotion improved hair density and thickness in patients with mild pattern hair loss over six months.

This review discusses the regulatory roles of lysophospholipids like LPA and S1P in diseases such as fibrosis, neuropathic pain, and cancer, but reports no new clinical results.

This study found that in Japanese, German, and American females, changes in hair lipid patterns with age may reflect alterations in sebum excretion and affect hair texture.

This study found that sebaceous-gland-derived glycerol significantly contributes to stratum corneum hydration in mice with sebaceous gland deficiencies.

This study suggests that heparan sulfate is crucial for regulating hair follicle formation, cycling, and gland morphogenesis, with its ablation leading to continuous hair growth and increased gland activity in mice.

This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.

This article reviews sebaceous immunobiology and highlights the complex role of sebaceous glands and sebocytes in skin barrier function and inflammation, particularly in acne pathogenesis, but reports no new results.

This study investigated lipid loss in hair caused by surfactants and found that surface and internal modifications can significantly protect different lipids from depletion, with internal modification preventing 52.0 to 81.3% of lipids in certain groups.

This study reports that a plant extract from Orobanche rapum can stimulate skin rejuvenation and protect cutaneous microbiota, potentially creating healthier skin.

This review highlights Stephen Rothman's influential role in transforming dermatology into a rigorous scientific discipline but does not report new clinical research outcomes.

This study reports new fluorogenic ceramidase substrates and highlights RBM14C24:1 as an efficient substrate for neutral ceramidase, while RBM15C18:1 is the best probe for measuring ACER1 and ACER2 activities, potentially aiding high-throughput screening for ceramidase inhibitors.

This news review reports on the latest developments in lipid technology but presents no new research findings.

This study found that knockout mice lacking SMS1 showed reduced body weight and hair loss, indicating a role for SMS1 in normal growth and hair health.

This study found that activating the hexosamine pathway increased hyaluronic acid secretion and hair follicle stem cell numbers in vitro, suggesting its role in modulating skin homeostasis.

This study found no significant differences in phosphatide distribution between normal and cancerous mouse epidermis during different stages of growth, despite variations in total phosphatide levels.

This study reviews the emerging role of protein S-palmitoylation in dermatology, highlighting its impact on skin functions like inflammation and barrier maintenance, and evaluating its potential as a therapeutic target for skin disorders such as alopecia and psoriasis.

Applying pseudoceramide improved skin and hair health.

This study found that skin sulfhydryl oxidase plays a role in keratinization and may contribute to skin's protective functions, with its expression influenced by irritants and differentiation modifiers.

In this study, a high-fat, high-cholesterol diet in atherosclerotic mice led to skin inflammation and hair problems, which could be reversed by inhibiting glycosphingolipid synthesis.

In this study, researchers found that disrupting desmoglein 3 signaling in a mouse model of pemphigus vulgaris activates normally quiescent hair follicle stem cells, compromising their multipotency but prompting a regenerative response that restores stem cell function and structures.

This article discusses how activating the hexosamine pathway may enhance skin homeostasis by increasing hyaluronic acid secretion and supporting hair follicle stem cell self-renewal, but reports no new results.